2022-09-162022-09-162007-07Akkaya, C. vd. (2007). "Urticaria and angio-oedema due to ziprasidone". Journal of Psychopharmacology, 21(5), 550-552.1461-72850269-8811https://doi.org/10.1177/0269881106075273https://journals.sagepub.com/doi/10.1177/0269881106075273http://hdl.handle.net/11452/28790Antipsychotic medications are commonly associated with adverse cutaneous reactions (ACRs) in approximately 5% of patients. Angio-oedema accompanying unticaria is one of the most serious ACRs. The 36-year-old female patient who was diagnosed with 'Paranoid schizophrenia' 6 years ago, was commenced on ziprasidone 120 mg/day. On day 30 of the treatment, the patient presented urticarial papules and plaques all over the body and angio-oedema in the face. The patient was diagnosed as 'Urticaria+Angio-oedema'. The development of ACRs after the initation of ziprasidone monotherapy, disappearance of Lesions after the discontinuation of this antipsychotic, and positive intradermal skin test all suggests a possible causal relationship between ACRs and ziprasidone. To our knowledge, this is the first reported case of unticaria and angio-oedema due to ziprasidone monotherapy. Ziprasidone is a valid and effective choice amongst antipsychotic medications, but this case calls for caution regarding ACRs at the time of prescribing.eninfo:eu-repo/semantics/closedAccessAngio-oedemaAdverse cutaneous reactionsRisperidoneUrticariaZiprasidoneAntipsychotic agentsAdultAngioneurotic edemaFemaleHumansPiperazinesSchizophrenia, paranoidThiazolesUrticariaArticle0002487932000132-s2.0-3454712457755055221517446198Clinical neurologyNeurosciencesPharmacology & pharmacyPsychiatryDexamphetamine; Edema; Adrenergic Receptor Stimulating AgentAdultBetamethasone sodium phosphateBiperidenFexofenadineHaloperidolPheniramine maleateZiprasidoneZuclopenthixolArticlePriority journalAngioneurotic edemaDrug withdrawalPhysical examinationCase reportCausal attributionConsultationDermatologyDrug dose increaseFemaleParanoid schizophreniaFace edemaHumanMonotherapyPapuleInvoluntary movementRigiditySide effectSingle drug doseSkin testSymptomUrticaria