Yeşildemir, ÖzgeAkdevelioglu, YaseminDuyan Camurdan, AysuCuhaci Cakir, BaharErdemli Kose, Selinay BasakArca Cakir, DenizYirun, AnilBalci Ozyurt, AylinSabuncuoglu, SunaErkekoglu, Pinar2024-10-162024-10-162022-12-240148-0545https://doi.org/10.1080/01480545.2022.2160456https://www.tandfonline.com/doi/full/10.1080/01480545.2022.2160456https://hdl.handle.net/11452/46527This study aimed to estimate and compare dietary exposure to bisphenol A (BPA) in exclusively breastfed (EBF) and breastfed plus formula-fed (BF + FF) infants. A total of 70 mothers and their 0-6 month-old infants (40 in the EBF group and 30 in BF + FF group) were included in the study. After the questionnaire form was applied to the mothers, maternal breast milk, infant formula, and infant urine were collected from mother-infant dyads. Total BPA levels in breast milk, infant formula, and infant urine samples were analyzed by the high-pressure liquid chromatography (HPLC). While BPA was detected in 92.5% of the breast milk samples in the EBF group (mean +/- SD = 0.59 +/- 0.29 ng/mL), BPA was detected in all of the breast milk samples in the BF + FF group (mean +/- SD= 0.72 +/- 0.37 ng/mL) (p < 0.05). Similarly, 100% of the infant formula samples in the BF + FF group had detectable levels of BPA (mean +/- SD = 7.54 +/- 1.77 ng/g formula). The mean urinary BPA levels in the EBF infants (4.33 +/- 1.89 mu g/g creatinine) were not statistically different from the BF + FF infants (5.81 +/- 0.11 mu g/g creatinine) (p > 0.05). The average daily BPA intake in EBF infants (0.18 +/- 0.13 mu g/kg body weight (bw)/day) was found to be significantly higher than in BF + FF infants (0.12 +/- 0.09 mu g/kg bw/day) (p < 0.05). The estimated dietary intakes of BPA for infants in both groups were below the temporary tolerable daily intake (t-TDI) (4 mu g/kg bw/day). Consequently, BPA intake of EBF and BF + FF infants were within safe daily limits during the first six months of life.eninfo:eu-repo/semantics/closedAccessTandem mass-spectrometryEnvironmental phenolsHuman-milkGas-chromatographyLiquid-extractionPowdered milkFoodUrinaryContaminantsDerivativesBisphenol aUrineExposureExclusive breastfeedingFormula-fedScience & technologyPhysical sciencesLife sciences & biomedicineChemistry, multidisciplinaryPharmacology & pharmacyToxicologyChemistryArticle00090397630000125326347310.1080/01480545.2022.21604561525-6014