2023-11-032023-11-032018-05-22Poyrazoğlu, Ş. vd. (2018). ''Incidence of type 1 diabetes in children aged below 18 years during 2013-2015 in northwest Turkey''. Journal of Clinical Research in Pediatric Endocrinology, 10(4), 336-342.1308-57271308-5735https://doi.org/10.4274/jcrpe.0025https://cms.galenos.com.tr/Uploads/Article_18127/JCRPE-10-336-En.pdfhttp://hdl.handle.net/11452/34779Çalışmada 55 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır.Objective: To assess the incidence of type I diabetes mellitus (T1DM) in children under 18 years of age in the northwest region of Turkey during 2013-2015. Methods: All newly diagnosed T1DM cases were recorded prospectively during 2013-2015. Total, as well as gender and age group specific (0-4, 5-9. 10-14 and 15-17 age) mean incidences per 100,000 per year were calculated. Results: There were 1,773 patients diagnosed during 2013-2015 (588 cases in 2013, 592 cases in 2014, 593 cases in 2015). Of these, 862 (48.6 %) were girls and 911 (51.4%)were boys. The mean age at diagnosis was 9.2 +/- 4.2 years and it was not significantly different between girls (9.0 +/- 4.1 years) and boys (9.4 +/- 4.4 years) (p = 0.052). The crude mean incidence was 8.99/100.000 confidence interval (CI) (95% CI: 8.58-9.42). Although mean incidence was similar between boys [8.98/100.000 (CI: 8.40 to 9.58)] and girls [9.01/100.000 (CI: 8.42 to 9.63)], there was male predominance in all groups except for 5-9 year age group. The standardized mean incidence was 9.02/100.000 according to the World Health Organization standard population. The mean incidence for the 0-4, 5-9, 10-14 and 15-17 age groups was 6.13, 11.68, 11.7 and 5.04/1 00.000 respectively. The incidence of T1DM was similar over the course of three years (p = 0.95). A significant increase in the proportion of cases diagnosed was observed in the autumn-winter seasons.eninfo:eu-repo/semantics/openAccessEndocrinology & metabolismPediatricsType 1 diabetes mellitusChildhoodIncidenceRapidly rising incidenceSeasonal-variationNationwide incidenceMellitusOnsetPrevalenceTrendsTimeEpidemiologyDiagnosisAdolescentChildChild, preschoolCohort studiesDiabetes mellitus, type 1FemaleGeographyHumansIncidenceInfantInfant, newbornMaleRegistriesSeasonsTurkeyIncidence of type 1 diabetes in children aged below 18 years during 2013-2015 in northwest TurkeyArticle0004516670000062-s2.0-8505754669133634210429789274Endocrinology & metabolismPediatricsInsulin Dependent Diabetes Mellitus; Enterovirus; Nonobese Diabetic MouseInsulinAdolescentArticleAutumnChildChildhoodCystic fibrosisDiabetes mellitusFemaleHealth care systemHumanHyperglycemiaInsulin dependent diabetes mellitusLifestyleMaleNon insulin dependentDiabetes mellitusRisk factorSeasonal variationSex differenceTopographyTurkey (republic)UrbanizationWinterWorld health organizationCohort analysisGeographyIncidenceInfantInsulin dependent diabetes mellitusNewbornPreschool childRegisterSeasonStatistics and numerical dataTurkey (bird)