Tüydeş, OktayYüksel, AhmetŞenol, SefaAkarsu, Serkan2022-10-272022-10-272016-06Tok, M. vd. (2016). "Early-term outcomes for treatment of saphenous vein insufficiency with N-butyl cyanoacrylate: A novel, non-thermal, and non-tumescent percutaneous embolization technique". Heart Surgery Forum, 19(3), E118-E122.1098-35111522-6662https://doi.org/10.1532/hsf.1496https://journal.hsforum.com/index.php/HSF/article/view/1496http://hdl.handle.net/11452/29235Background: The purpose of this study was to present early-term outcomes of VariClose r Vein Sealing System, which is a novel, non-thermal, and non-tumescent percutaneous embolization technique for treatment of saphenous vein insufficiency. Methods: Between March 2014 and July 2015, 189 saphenous veins in 141 patients were treated with Variclose Vein Sealing System containing n-butyl cyanoacrylate. Pre-, intra-, post-procedural, and follow-up data of patients were collected and retrospectively reviewed. Results: Mean age of patients was 42.5 +/- 14.0 years, of which 53% were female. Technical success rate of intervention was 98.9%. Mean procedure time was 14.3 +/- 7.5 minutes. Eighty-nine percent of patients (n = 126/ 141) were available at mean follow-up time of 6.7 months. Mean Venous Clinical Severity Score was significantly improved from 8.3 +/- 2.2 at pre-procedure period to 3.3 +/- 1.8 at follow-up. No complete recanalization was observed, but 2 patients were presented with partial recanalization during follow-up. The complete occlusion rate was 98.4%. No serious adverse event related to procedure was observed. Conclusion: Variclose Vein Sealing System appears to be safe and effective in treatment of saphenous vein insufficiency. Further randomized studies with long-term outcomes are required for determining optimal treatment modality in patients with saphenous vein insufficiency.eninfo:eu-repo/semantics/closedAccessCardiovascular system & cardiologySurgeryThermal ablationVaricose-veinsFollow-upPolidocanol foamGreatSclerotherapyMulticenterTrialAdhesiveRefluxAdultAgedEmbolization, therapeuticFemaleHumansMaleMiddle agedRetrospective studiesSaphenous veinVaricose veinsVenous insufficiencyYoung adultArticle0003847933000082-s2.0-84977652435E118E12219327355146Cardiac & cardiovascular systemsSurgeryVaricosis; Saphenous Vein; SclerotherapyAntibiotic agentEnbucrilateNonsteroid antiinflammatory agentAdultAgedArticleArtificial embolizationClinical effectivenessControlled studyDevice embolizationEcchymosisFemaleFemoral veinFollow upHumanIntraoperative periodMajor clinical studyMaleMean venous clinical severity scoreOcclusionOperation durationPercutaneous emblization techniquePostoperative periodPreoperative periodPriority journalRating scaleRecanalizationReinterventionRetrospective studySafetySaphenofemoral junctionSaphenous veinSaphenous vein insufficiencyThrombophlebitisTreatment durationTreatment outcomeValsalva maneuverVasospasmVein diameterVein insufficiencyArtificial embolizationMiddle agedProceduresVaricose veinsVenous InsufficiencyYoung adult