Mahboub, BassamBeji, MajedNejjari, ChakibTageldin, Mohamed AwadKhan, Javaid AhmedNafti, SalimObeidat, Nathir M.Sayıner, AbdullahWali, SirajRashid, NaumanEl Hasnaoui, Abdelkader2022-03-312022-03-312012-12Uzaslan, E. vd. (2012). "The burden of chronic obstructive pulmonary disease in the Middle East and North Africa: Results of the BREATHE study". Respiratory Medicine, 106(Supplement 2), S45-S59.0954-61111532-3064https://doi.org/10.1016/S0954-6111(12)70014-8https://www.sciencedirect.com/science/article/pii/S0954611112700148http://hdl.handle.net/11452/25489COPD is a progressive pulmonary disease which may have a profound impact on general health status and quality of life. This article presents data on the burden of COPD obtained from the BREATHE study in the Middle East, North Africa and Pakistan. This study was a large general population survey of COPD conducted in eleven countries of the region using a standardised methodology. A total of 62,086 subjects were screened, of whom 2,187 fulfilled the "epidemiological" definition of COPD. Data on symptoms, perceived disease severity, impact on work, limitations in activities and psychological distress were collected. 1,392 subjects were analysable of whom 661 (47.5%) reported experiencing an exacerbation of their respiratory condition, 49.4% reported comorbidities and 5.5% reported severe breathlessness as measured with the MRC breathlessness questionnaire. The degree of breathlessness, as well as the perceived severity, was correlated with the overall disease impact as measured with the COPD Assessment Test (p < 0.001). 374 subjects (28.4%) reported that their respiratory condition prevented them from working and this proportion rose to 47.8% in subjects who perceived their respiratory condition as severe. 47.9% of subjects reported difficulties in normal physical exertion, 37.5% in social activities and 31.7% in family activities. Psychological distress was reported by between 42.3% and 53.2% of subjects, depending on the item. In conclusion, the burden of COPD is important, and covers central aspects of daily life. For this reason, physicians should take time to discuss it with their patients, and ensure that the management strategy proposed addresses all their needs.eninfo:eu-repo/semantics/openAccessCardiovascular system & cardiologyRespiratory systemCOPDBurden of diseaseMiddle eastNorth AfricaImpactExacerbationComorbidityPsychological distressCopd assessment testDiabetes-mellitusAsthma insightsRisk-factorsPrevalenceImpactPopulationDisabilityMortalityDiagnosisActivities of daily livingAdultAfrica, northernAgedComorbidityCost of illnessCross-sectional studiesFemaleHealth resourcesHumansMaleMiddle agedMiddle eastPakistanPulmonary disease, chronic obstructiveQuality of lifeSeverity of illness indexStress, psychologicalWorkArticle0003141355000072-s2.0-84872017307S45S59106Supplement 223290704Cardiac & cardiovascular systemsRespiratory systemChronic Obstructive Lung Disease; Spirometry; Forced Expiratory VolumeAdl disabilityAdultAlgeriaArticleAsthmaCardiovascular diseaseChronic bronchitisChronic obstructive lung diseaseComorbidityConsultationCoughingDaily life activityDiabetes mellitusDisease burdenDisease exacerbationDisease severityDistress syndromeDyspneaEgyptEmergency careEmployment statusExerciseFemaleGeneral aspects of diseaseHealth care systemHealth statusHospitalizationHumanJordanLebanonMajor clinical studyMaleMiddle eastMoroccoNorth AfricaPakistanParttime employmentPriority journalQuality of lifeSaudi ArabiaSexual intercourseSleepSmoking habitSocial behaviorSyrian Arab republicTunisiaTurkey (republic)United Arab emiratesWork capacity