2021-11-262021-11-262009Türkel, S. ve Ener, B. (2009). "Isolation and characterization of new Metschnikowia pulcherrima strains as producers of the antimicrobial pigment pulcherrimin". Zeitschrift fur Naturforschung - Section C Journal of Biosciences, 64(5-6), 405-410.0939-5075https://doi.org/10.1515/znc-2009-5-618http://hdl.handle.net/11452/22813Metschnikowia pulcherrima is a highly effective biocontrol yeast due to its pigment pulcherrimin that accumulates in the cells and in the growth medium. Three different strains of M. pulcherrima were isolated from local grapes. The yeast isolates were characterized on the basis of their biochemical, physiological and ITS1-5.8 s rDNA-ITS2 region. Based on the obtained results, the M. pulcherrima isolates were identified as new strains of M. pulcherrima. Strong antagonistic activities of the M. pulcherrima strains on the human pathogens Proteus vulgaris, Escherichia coli, Candida albicans, Candida parapsilosis, Candida krusei, and Trichosporon mucoides were determined. In addition, antagonistic effects of these M. pulcherrima strains were also tested against Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Trichoderma spp., Paecilomyces spp., and Bipolaris spp. and it was shown that the three different strains of M. pulcherrima also have an antagonistic effect on the growth of these fungal species at different extents. This study showed that all three strains of M. pulcherrima produce the same amount of the pigment pulcherrimin, but their antimicrobial activities on different microorganisms show important variations.eninfo:eu-repo/semantics/closedAccessBiocontrolPulcherriminAntagonistic YeastsSpontaneous fermentationYeast populationsBiocontrolMechanismsFungiResistanceDiversityStorageGrapesAppleBiochemistry & molecular biologyPharmacology & pharmacyAspergillus flavusAspergillus fumigatusAspergillus nigerBipolarisCandida albicansCandida parapsilosisEscherichia coliIssatchenkia orientalisMetschnikowia pulcherrimaProteus vulgarisTrichodermaTrichosporon mucoidesVitaceaeAmino acids, sulfurAnti-bacterial agentsAnti-infective agentsDNA primersDNA, fungalDNA, ribosomalEscherichia coliFungiGene amplificationHumansMetschnikowiaPiperidinesPolymerase chain reactionProteus vulgarisVitisAntifungal agentsArticle0002688267000182-s2.0-70349313603405410645-619678547Biochemistry & molecular biologyPharmacology & pharmacyPyrazine Derivative; Favipiravir; DiketopiperazinesAntifungal agentAntiinfective agentFungal DNAPiperidine derivativePrimer DNAPulcherrimineRibosome DNASulfur amino acidArticleChemistryDrug effectEscherichia coliFungusGene amplificationGeneticsGrapeHumanIsolation and purificationMetschnikowiaMicrobiologyPolymerase chain reactionProteus vulgaris