Giangaspero, MassimoApicella, Claudio2023-01-112023-01-112018-07-26Giangaspero, M. vd. (2018). ''Who's who in the Bovine viral diarrhea virus type 1 species: Genotypes L and R''. Virus Research, 256, 50-75.0168-17021872-7492https://doi.org/10.1016/j.virusres.2018.07.009https://www.sciencedirect.com/science/article/pii/S0168170218300418http://hdl.handle.net/11452/30377The bovine viral diarrhea virus type 1 species is responsible for cosmopolitan diseases affecting cattle and other ruminants, with relevant impact on animal production. The species presents high genomic heterogeneity, with implications on control and prophylactic programs. Genomic traits of different genetic groups are often related to geographic origin. Atypical sequences have been reported from Pestivirus isolates originated from cattle in Turkey. Based on phylogenetic analysis of 5' untranslated region and Npro and secondary structure analysis of the 5'-UTR RNA, Turkish isolates have been segregated in two distinct genotypes. Out of the twenty-three identified BVDV-1 genotypes, the Turkish clusters, named L and R or 1.16 and 1.14, according to palindromic nucleotide substitution genotyping method, represent genomic clusters so far, not described elsewhere, suggesting geographic segregation. In order to avoid confusion in the current taxonomy of the species, nomenclature of described homonymous genotypes, referred to different genomic clusters, should be corrected.eninfo:eu-repo/semantics/closedAccessVirologyBovine viral diarrhea virus type 1Genotypes L and RNomenclaturePalindromic nucleotide substitutionsPestivirusSecondary structurePalindromic nucleotide substitutionsGenetic diversity5'-untranslated regionMoleculer characterization5'-untranslated regionPyhlogenetic analysisGenus pestivirusCattle herds1 isolateIdentification5' untranslated regionsAnimalsBovine virus diarrhea-mucosal diseaseCattleCluster analysisDiarrhea virus 1, bovine viralGenetic variationGenotypePhylogeographySequence analysis, DNASequence homologyTurkeyViral proteinsArticle0004471118000092-s2.0-85051401448507525630056173VirologyBovine Viral Diarrhea Viruses; Pestivirus; CattleNpro protein, bovine viral diarrhea virusViral protein5' untranslated regionArticleBovine viral diarrhea virus 1Bovine viral diarrhea virus 1 genotype LBovine viral diarrhea virus 1 genotype RInternal ribosome entry siteNomenclatureNonhumanPhylogenyPriority journalProtein secondary structureTaxonomyVirus isolationAnimalBovineBovine viral diarrheaBovine viral diarrhea virus 1ClassificationCluster analysisDNA sequenceGenetic variationGeneticsGenotypeIsolation and purificationPhylogeographySequence homologyTurkey (bird)Virology