Gürcan, ŞabanTikveşli, MelekÜstündaǧ, Sedat2022-06-202022-06-202013Gürcan, Ş. vd. (2013). "A case report on aspergillus lentulus pneumonia". Balkan Medical Journal, 30(4), 429-431.2146-31232146-3131https://doi.org/10.5152/balkanmedj.2013.8572https://dergipark.org.tr/tr/pub/bmj/article/50460http://hdl.handle.net/11452/27319Bu çalışma, 03-07 Kasım 2012 tarihleri arasında Aydın[Türkiye]’da düzenlenen 35. Turkish National Congress of Microbiology’da bildiri olarak sunulmuştur.Background: Aspergillus lentulus was described as a new species in 2005 but it was isolated from Turkey for the first time. Case report: A. lentulus was isolated as the cause of pneumonia from a patient who had renal transplantation 4 months ago. The patient received immunosuppressive treatment after transplantation. A. lentulus was isolated from his sputum as an agent in pneumonia developed 4 months after the transplantation. Leukocytes, blastospores, and hyphae were seen in both Gram- and Giemsa-stained smears of the sputum. The isolate was identified by using the Maren A. Klich algorithm and molecular methods and confirmed by the reference laboratory of the CBS Fungal Biodiversity Centre ( The Netherlands). In the susceptibility tests of the isolate, minimal inhibitory concentrations for amphotericin B, voriconazole, posaconazole, and caspofungin were found to be 0.5 mu g/mL, 0.25 mu g/mL, 0.125 mu g/mL, and 0.25 mu g/mL, respectively. The patient recovered with voriconazole treatment (2x200 mg/day). Conclusion: The use of the molecular tests is important for identification of A. lentulus strains because they are very easily confused with A. fumigatus strains according to phenotypic characteristics.eninfo:eu-repo/semantics/openAccessGeneral & internal medicineInvasive pulmonary aspergillosisIimmunocompromised hostAspergillus lentulusSection fumigatiAntifungal susceptibilityInvasive aspergillosisDemethylase cyp51aIdentificationPatientSpainSpp.Article0003292063000152-s2.0-8489161592142943130425207153Medicine, general & internalIsavuconazonium; Antifungal Agents; VoriconazoleAmphotericin BCaspofunginCorticosteroidMycophenolic acid 2 morpholinoethyl esterPosaconazoleTacrolimusVoriconazoleAdultAntifungal susceptibilityArticleAspergillusAspergillus lentulusBlastosporeCadaver kidneyCase reportChronic kidney failureContinuous ambulatory peritoneal dialysisCoughingFemaleFungus hyphaeFungus identificationFungus isolationFungus sporeGiemsa stainGram stainingHumanImmunosuppressive treatmentIncubation timeKidney graft rejectionKidney transplantationLaboratory testLeukocyteLow drug doseLung aspergillosisMinimum inhibitory concentrationMolecular diagnosisNonhumanPhenotypePostoperative periodSputum smearTreatment durationTurkey (republic)