2023-02-232023-02-232020-03-03Yazıcı, B. vd. (2020). "Isolated and transient nuclear midbrain blepharoptosis in a young and healthy adult". Neuro-Ophthalmology, 44(2), 111-113.0165-81071744-506Xhttps://doi.org/10.1080/01658107.2019.1588336https://www.tandfonline.com/doi/full/10.1080/01658107.2019.1588336http://hdl.handle.net/11452/31163A 32-year-old otherwise healthy man presented with acute-onset bilateral blepharoptosis of 6 days' duration. On examination, he had severe ptosis bilaterally and mildly restricted abduction in the left eye. Brain magnetic resonance imaging showed a 10-mm-diameter lesion in the dorsal midbrain. The ptosis resolved spontaneously within two weeks. Systemic investigation did not uncover any aetiological factor. During 70 months' follow-up, neither any systemic disease nor ptosis relapse developed. Isolated nuclear midbrain ptosis has been previously reported in a few patients and these had neoplastic or inflammatory causes. In this patient, spontaneous resolution of the nuclear ptosis within weeks suggested that the underlying cause might be isolated ischaemic damage to the central caudal nucleus.eninfo:eu-repo/semantics/openAccessNuclear blepharoptosisMesencephalonTransient ptosisMidbrain lesionBilateral ptosisInfarctionNeurosciences & neurologyOphthalmologyArticle0005193070000082-s2.0-8506325971011111344232395159Clinical neurologyOphthalmologyDiplopia; Abducens Nerve Disease; Oculomotor NervesAdultArticleCase reportClinical articleCongenital blepharoptosisConsultationContrast enhancementDisease durationDisease severityEye examinationEye movementFollow upHumanMaleMesencephalonNeuroimagingNuclear magnetic resonance imagingPalpebral fissurePtosis (eyelid)SomnolenceSystemic diseaseUpper respiratory tract infectionVisual acuity