Baykan, BetülErtaş, MustafaSiva, AkselSaip, Sabahattin2021-12-012021-12-012012-10Karlı, N. vd. (2012). "Impact of sex hormonal changes on tension-type headache and migraine: A cross-sectional population-based survey in 2,600 women". Journal of Headache and Pain, 13(7), 557-565.1129-23691129-2377https://doi.org/10.1007/s10194-012-0475-0https://pubmed.ncbi.nlm.nih.gov/22935969/https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1007/s10194-012-0475-0http://hdl.handle.net/11452/22925Sex hormones have some implications on headaches. The objective of the study was to investigate the effects of hormonal changes comparatively on tension-type headache (TTH) and migraine, in a population-based sample. A nationwide face-to-face prevalence study was conducted using a structured electronic questionnaire. 54.3 % of the migraineurs reported that the probability of experiencing headache during menstruation was high, whereas 3.9 % had headache only during menstruation. Forward logistic regression analysis revealed that menstruation was a significant trigger for migraine in comparison to TTH. On the other hand, nearly double the number of TTH sufferers reported "pure menstrual headache" compared to migraineurs (p = 0.02). Menstrual headaches caused significantly higher MIDAS grades. One-third of the definite migraineurs reported improvement during pregnancy and oral contraceptives significantly worsened migraine. Menopause had a slight improving effect on migraine compared to TTH. Sex hormonal changes have major impacts particularly on migraine; however, the effects of hormonal fluctuations on TTH should not be underestimated.eninfo:eu-repo/semantics/openAccessNeurosciences & neurologySex hormonesHeadacheMigraineTension-type headacheMenopauseMenstruationReproductive life eventsUnderstanding mechanismsOvarian hormonesMenstrual-cycleDouble-blindPrevalenceAuraPathogenesisPregnancyAttacksArticle0003089602000082-s2.0-8487034656855756513722935969Clinical neurologyNeurosciencesMigraine Disorders; Headache; TryptaminesOral contraceptive agentSex hormoneAdultAgedArticleFemaleHealth surveyHumanLogistic regression analysisMajor clinical studyMenopauseMenstrual migraineMigraineMigraine disability assessment questionnairePregnancyPriority journalQuestionnaireTension headache