Yılmaz, Yusuf2021-12-242021-12-242009-09-14Yılmaz, Y. ve Dolar, E. (2009). "Biomarkers for noninvasive biochemical diagnosis of nonalcoholic steatohepatitis: Tools or decorations?". World Journal of Gastroenterology, 15(34), 4346-4347.1007-9327https://doi.org/10.3748/wjg.15.4346https://www.wjgnet.com/1007-9327/full/v15/i34/4346.htmhttp://hdl.handle.net/11452/23556In light of the growing epidemics of nonalcoholic fatty liver disease (NAFLD), identification and validation of the novel biochemical surrogate markers for nonalcoholic steatohepatitis (NASH) are paramount to reduce the necessity for liver biopsy. The availability of such markers has tremendous potential to radically alter the management strategies of NAFLD patients and to monitor the disease activity. Although current biomarkers do not entirely fulfill the many requirements for the identification of patients with NASH, they should not discourage our quest, but remind us that we need to cognize the challenges ahead.eninfo:eu-repo/semantics/openAccessBiomarkersLiver biopsyNonalcoholic fatty liver diseaseNonalcoholic steatohepatitisFatty liver-diseaseValuesGastroenterology & hepatologyBiological markersFatty liverHepatitisHumansLiverTransaminasesArticle0002698149000192-s2.0-7034956952843464347153419750583Gastroenterology & hepatologyFatty Liver; Proton Density (Concentration); Keratin-18Alanine aminotransferaseAspartate aminotransferaseBiological markerCytokeratin 18AminotransferaseBiological markerAlanine aminotransferase blood levelArticleAspartate aminotransferase blood levelBayes theoremClinical practiceDiagnostic accuracyDisease activityFalse negative resultHumanLaboratory diagnosisLiver biopsyNon invasive procedureNonalcoholic fatty liverPatient monitoringPredictionReliabilityReproducibilitySensitivity and specificityFatty liverHepatitisLiverMetabolismNote