2022-01-282022-01-282011-01Çetinkaya, M. vd. (2011). "Early left ventricular diastolic dysfunction in premature infants born to preeclamptic mothers". Journal of Perinatal Medicine, 39(1), 89-95.https://doi.org/10.1515/JPM.2010.126http://hdl.handle.net/11452/24312Aim: To evaluate the cardiac function in premature infants born to preeclamptic mothers and its clinical consequences. Methods: This was a prospective observational cohort study performed in a tertiary neonatal intensive care unit. Fifty-three premature infants born to preeclamptic mothers comprising the study group were evaluated and compared with 42 premature infants born to normotensive mothers (control group). Relationship between echocardiographic measures and neonatal morbidity were assessed as the main outcome measures. Results: Left ventricle end-diastolic dimension (LVEDD), peak flow velocities during early diastole (peak E wave), peak flow velocities during atrial contraction (peak A wave), and peak E/A ratio were significantly lower in the study group. Within the study group, these parameters were also significantly lower in infants with respiratory problems. LVEDD was significantly smaller in preeclamptic infants with intrauterine growth retardation (IUGR). Conclusion: Left ventricle diastolic dysfunction (LVDD) was detected in premature infants born to preeclamptic mothers in the first week after delivery. LVDD was associated with higher incidence of respiratory problems, transient tachypnea of the newborn, longer duration of oxygen requirement, and IUGR.eninfo:eu-repo/semantics/closedAccessObstetrics & gynecologyPediatricsDiastolic dysfunctionEchocardiographyNewbornPreeclamptic motherPrematureCardiac troponin-tTransient tachypneaPerinatal asphyxiaAlveolar hypoxiaEarly-onsetManagementDiagnosisNewbornEchocardiographyIschemiaCase-control studiesFemaleHumansInfant, newbornInfant, prematureInfant, premature, diseasesMalePre-eclampsiaPregnancyProspective studiesVentricular dysfunction, leftArticle0002861809000152-s2.0-78651353067899539121142411Obstetrics & gynecologyPediatricsTroponin T; Asphyxia; Apgar ScoreArticleCohort analysisControlled studyDeliveryDiastoleDiastolic dysfunctionEchocardiographyFemaleHeart atrium contractionHeart functionHeart left ventricleHumanIntrauterine growth retardationMajor clinical studyMaleNewbornNewborn intensive care nursingNewborn morbidityObservational studyOxygen consumptionPreeclampsiaPrematurityPriority journalProspective studyRespiratory tract diseaseTachypneaTertiary health care