2022-04-212022-04-212003-05Ersoy, A. vd. (2003). “Survival analysis of the factors affecting in mortality in injured patients requiring dialysis due to acute renal failure during the Marmara earthquake: Survivors vs non-survivors”. Clinical Nephrology, 59(5), 334-340.0301-0430https://doi.org/10.5414/CNP59334http://hdl.handle.net/11452/25934Background: We reviewed medical records of dialyzed patients admitted to our hospital after the Marmara earthquake and evaluated the factors affecting mortality in survivors and non-survivors according to the survival times. Patients and methods: Crush syndrome ( CS) was diagnosed in 110 patients. Dialysis treatment was initiated in 60 patients; 21 of all died. The patients were divided into 2 groups which consisted of 39 survivors ( Group A, 25 male, 14 female, mean age: 31 +/- 2.2 years) and 21 nonsurvivors ( Group B, 9 male, 12 female, mean age: 27 +/- 3.0 years). Victims treated by any form of renal replacement therapy, including daily or intermittant hemodialysis and/or continuous venovenous hemodiafiltration. Clinical and laboratory findings were recorded regularly. Statistical analysis was performed with Kaplan-Meier method, log rank test and Cox regression analysis for the survival functions. Results: APACHE II scores were 13.5 +/- 0.5 for Group A and 13 +/- 0.9 for Group B. Dialysis support was started to patients in Group A in a mean period of 2.8 +/- 0.2 days and in Group B in a mean period of 3.7 +/- 0.6 days after the earthquake ( p > 0.05). The most frequent site of trauma was lower extremity (61.5%) and upper + lower extremities (23%) in Group A, and lower extremity (38.1%) and trunk + lower extremity (23.8%) in Group B. The frequencies of abdominal trauma, pelvic fracture and thoracic trauma in Group B were 23.8%, 19% and 14.2%, respectively. Multiple trauma was more frequent in Group B than in Group A (42.8% vs 2.5%). The rates of fasciotomy, amputation and surgery were similar in both groups. The frequency of sepsis was higher in nonsurvivors. In our center, the overall mortality rate was 8%, mortality rate in CS was 21% and in dialyzed patients it was 35%. Mortality was mainly associated with sepsis. Survival periods (52.3 +/- 4.0 days) in Group A were longer than in Group B (17.3 +/- 2.5 days). With Cox regression analysis, the parameters such as systolic hypotension on admission, female gender, high serum peak creatine kinase (> 20,000 U/l) and multiple trauma including thoracic and abdominal regions, were factors increasing risk of mortality. Conclusion: As a result, sepsis, multiple trauma and severe crush injury were the main factors increasing mortality risk in dialyzed injuries after the earthquake.eninfo:eu-repo/semantics/closedAccessUrology and nephrologyCrush syndromeEarthquakeRhabdomyolysisAcute renal failureDialysisSurvival timeMortalityHanshin-awaji earthquakeCritically-ill patientsCrush-syndromeArmenian earthquakeRhabdomyolysisManagementMorbidityVictimsArticle0001832293000042-s2.0-003863322533434059512779094Urology and nephrologyRhabdomyolysis; Earthquake; Acute Kidney InjuryAbdominal injuryAcute kidney failureAdultAmputationArm injuryClinical articleControlled studyCreatinine blood levelCrush syndromeDisease associationEarthquakeEpidemiological dataFasciotomyFemaleHemodialysis patientHospital admissionHumanKaplan Meier methodKidney transplantationLaboratory testLeg injuryMaleMedical recordMortalityMultiple traumaPelvis fracturePeritoneal dialysisRegression analysisReviewScoring systemSepsisSex differenceStatistical analysisSurvival rateSystolic hypertensionThorax injuryTurkey (republic)Creatine kinase