2021-10-122021-10-122002-10Ozan, H. vd. (2002). "Plasma anti-oxidant status and lipid profile in non-gravida women with a history of pre-eclampsia". Journal of Obstetrics and Gynaecology Research, 28(5), 274-279.1341-8076https://doi.org/10.1046/j.1341-8076.2002.00040.xhttps://obgyn.onlinelibrary.wiley.com/doi/full/10.1046/j.1341-8076.2002.00040.xhttp://hdl.handle.net/11452/22310Objective: To investigate the total plasma anti-oxidant status, the plasma lipid profile and the uterine artery Doppler velocity waveform in formerly pre-eclamptic women. Methods: Thirty-two formerly pre-eclamptic, non-gravida women constituted the study group, while 28 age-matched non-gravida women who had never had pre-eclampsia served as control subjects. On days 17-19 of their menstrual cycle, fasting plasma samples were collected for total anti-oxidant status (TAS) and lipid profile evaluation, and uterine artery Doppler velocity waveform studies were performed. Results were analyzed with Mann-Whitney U-test and Pearson correlation analysis. Results: There was no significant difference between the groups in means of the uterine artery Doppler velocity waveforms and the plasma lipid levels, but body mass index values were significant (P < 0.005). The TAS value was subnormal in 72% of the formerly pre-eclamptic group and in 35% of the control group. The mean plasma TAS value was 1.20 +/- 0.05mmol/L and was significantly lower in the study group when compared with the control group (P < 0.05). Conclusion: The current study reveals significantly decreased TAS in women with a history of pre-eclampsia, which may have an important role in pathophysiology.eninfo:eu-repo/semantics/closedAccessAntioxidantDopplerLipidPre-eclampsiaFree fatty-acidsPreeclampsiaRiskCirculationPeroxidesPregnancyObstetrics & gynecologyPregnancyAdultAntioxidantsFemaleHumansLipoproteinsPre-EclampsiaRegional blood flowUltrasonography, dopplerUterusArticle0001789663000072-s2.0-1874441503627427928512428698Obstetrics & gynecologyPlacenta Growth Factor; Pregnancy Toxemia; EndoglinAntioxidantCholesterolHigh density lipoprotein cholesterolLow density lipoprotein cholesterolLipidTriacylglycerolVery low density lipoprotein cholesterolAdultArterial pressureArticleBlood levelBlood samplingSystolic blood pressureBody massTriacylglycerol blood levelUterine arteryWaveformCholesterol blood levelClinical articleControlled studyCorrelation analysisData analysisDiastolic blood pressureDiet restrictionDisease associationFemaleHumanLaser doppler fowmetryLipid blood levelMenstrual cyclePathophysiologyPreeclampsiaRank sum testStatistical significance