Güler, Kazım2022-08-182022-08-182007-09Kaderli, B. vd. (2007). "Intravitreal triamcinolone improves recovery of visual acuity in nonarteritic anterior ischemic optic neuropathy". Journal of Neuro-Ophthalmology, 27(3), 164-168.1070-80221536-5166https://doi.org/10.1097/WNO.0b013e31814a5a9ahttps://journals.lww.com/jneuro-ophthalmology/Fulltext/2007/09000/Intravitreal_Triamcinolone_Improves_Recovery_of.2.aspxhttp://hdl.handle.net/11452/28249Background: The visual outcome in untreated non-arteritic anterior ischemic optic neuropathy (NAION) is dismal. Because intravitreal triamcinolone (IVTA) has shown promise in improving edematous retinal disorders, a pilot trial of this therapy in NAION was considered reasonable. Methods: Four eyes of 4 patients with severe visual loss due to NAION were treated with 4 mg IVTA (study group). The control group consisted of 6 consecutive patients with NAION who received no treatment. Patients were evaluated by the visual acuity and visual field measurements of the Early Treatment Diabetic Retinopathy Study (ETDRS) and fluorescein angiography. Results: All patients completed at least 9 months of follow-up. In the study group, the mean improvement in visual acuity were 4, 5.8, and 6.2 ETDRS lines at the first and third weeks and final visit, respectively. Optic disc swelling and leakage had markedly decreased at the first postinjection week and had disappeared by the third week examination in all eyes. In the control group, the mean improvements in visual acuity were 0, 0.7, and 1.3 ETDRS lines at the first and third weeks and final visit, respectively. Control eyes showed resolution of the optic disc swelling between the fourth week and third month visits. No marked change in visual field defects was observed in either group. Conclusions: IVTA provided relatively improved recovery of visual acuity and relatively rapid resolution of optic disc swelling in a small sample of patients with acute NAION. It did not provide visual field improvement. A larger trial is merited by the results of this small pilot studyeninfo:eu-repo/semantics/closedAccessNeurosciences & neurologyOphthalmologyAcetonideOptic nerveAgedAnti-inflammatory agentsFemaleHumansInjectionsMaleMiddle agedOptic diskPapilledemaOptic neuritisOptic neuropathy, ischemicPilot projectsRecovery of functionRetinal arteryTreatment outcomeTriamcinoloneVisual acuityArticle0002494137000042-s2.0-3474886092616416827317895814Clinical neurologyOphthalmologyAnterior Ischemic Optic Neuropathy; Ciliary Arteries; Optic Nerve DiseasesBrimonidineTriamcinolonePilot studyAdultPriority journalAgedNonarteritic anterior ischemic optic neuropathyCase reportArticleIntraocular hypertensionClinical trialControlled clinical trialControlled studyDiabetic retinopathyFemaleFluorescence angiographyFollow upHumanIschemic optic neuropathyMalePapilledemaVisual acuityVisual fieldVisual field defectVisual impairment