Regio- and diastereoselective synthesis of (E)-3-(2-aminochromen-4-yl)-6-aryl-substituted fulvenes

Koz, GamzeŞahin, Onur2023-06-092023-06-092016-05-03Koz, G. vd. (2016). "Regio- and diastereoselective synthesis of (E)-3-(2-aminochromen-4-yl)-6-aryl-substituted fulvenes". Zeitschrift fur Naturforschung-Section B Journal of Chemical Sciences, 71(9), 945-951.0932-07761865-7117https://doi.org/10.1515/znb-2016-0064https://www.degruyter.com/document/doi/10.1515/znb-2016-0064/htmlhttp://hdl.handle.net/11452/33000A practical base-catalyzed route was developed for the regio- and diastereoselective synthesis of (E)-3-aminochromene-6-aryl-disubstituted fulvenes in high yields up to 94% starting with the Michael addition of cyclopentadiene to 2-iminochromenes in the key step.eninfo:eu-repo/semantics/openAccessChemistryAminochromeneBase catalysisCyclopentadieneFulveneMichael additionFacile synthesisMichael reactionDerivatives2-amino-4h-chromenesCytotoxicityInhibitorsThioureaAgentsAddition reactionsCatalysisOlefinsAminochromeneBase catalysisCyclopentadienesFulveneMichael additionsStereoselectivityAnticancer drugsRegio- and diastereoselective synthesis of (E)-3-(2-aminochromen-4-yl)-6-aryl-substituted fulvenesArticle0003852911000032-s2.0-84990047450945951719Chemistry, inorganic & nuclearChemistry, organicTitanocene; Titanium Compounds; Ligands