Girgin, Nermin Kelebek2024-09-302024-09-302007-01-012146-6416https://hdl.handle.net/11452/45459Intensive care in patient with Guillain-barre syndrome Guillain-Barrke syndrome is an acute demyelinating neuropathy, that evolves after infectious disorders.. Although a definitive cause of GBS has not been identified, about two-thirds of patients have an infectious history within a 6 week period prior to the diagnosis, generally a flu-like episode or gastroenteritis.Symptoms typically start from the legs and ascend symmetrically to the upper body, and lead to progressive motor weakness and sensory abnormalities, and in some patients it turns up to complete quadriplejia. Dysautonomic symptoms such as cardiac disrhythmia, hypertension, hypotension, ileus or urinary retention are common and potentially harmful. Patients with GBS require intensive care support for the reasons primarily related to GBS (respiratory muscle failure, hemodynamic instability due to dysautonamia) and coexisting diseases indirectly. All patients need support care, and 25-30% of them also require mechanical ventilation therapy. The other treatment options such as plasma exchange, immunotherapy are helpful for alleviating the duration and severity of the disease. About 2-4 weeks after onset of symptoms, the weakness id prominent. The improvement of the disease may be insufficient, and about 4-15% of patients die. This article focused on general review the treatment of patients with GBS in intensive care unit.eninfo:eu-repo/semantics/closedAccessAcute respiratory-failureGuillain-barre syndromeIntensive careScience & technologyLife sciences & biomedicineCritical care medicineGeneral & internal medicineArticle0004222557000272147-267X556051