Uçar, Halil İbrahimDoǧan, Ömer FarukFarsak, BoraYorgancıoǧlu, Ali Cem2024-03-082024-03-082008-04Tok, M. vd .(2008). "Protective role of intracoronary shunt in off-pump coronary bypass operations". Saudi Medical Journal, 29(4), 573-579.0379-5284https://hdl.handle.net/11452/40288Objective: To investigate if there are any advantages in using intracoronary shunts compared to shuntless operations, in the context of whether it has a protective role for the myocardia. Methods: This prospective study, included 100 patients who underwent off-pump coronary bypass surgery at 2 different cardiovascular surgery departments, namely, the Social Security Ankara Ihtisas Hospital, and Hacettepe University Hospital, Turkey, between September 2002 and July 2006. Patients were divided into 2 groups. In group 1 (n=50) off-pump coronary bypass operations were performed with intracoronary shunts. In group 2 (n=50) shunts kinase, myoglobin, and troponin were stidied. Results: There were signicant increases in serum creatine kinase levels in group 2 at postoperative 6th, 12th, and 24th hours. In group 2, the increase of myoglobin was statistically significant at only the postoperative 24th hour. Troponin levels were significantly higher in group 2 at postoperative 6th, 12th, and 24th hours. Conclusion: There are some questions regarding myocardial protection while maintaining a bloodless secure surgical field in off-pump coronary surgery. However, use of intracoronary shunts provides distal coronary flow, and reduces the risk of myocardial ischemia, while maintaining a comfortable blood free anastomosis area.eninfo:eu-repo/semantics/closedAccessGeneral & internal medicineLeft-ventricular functionArtery-bypassCardiopulmonary bypassTroponin-tOn-pumpBeating heartGraft patencyOpcab surgeryRiskRevascularizationCoronary artery bypass, off-pumpCoronary vesselsCreatine kinaseFemaleHumansMaleMiddle agedMyoglobinProspective studiesTroponinArticle2-s2.0-4674911274957357929418382802Saudi Medical JournalOff Pump Coronary Surgery; Coronary Artery Bypass Graft; Bypass SurgeryBeta adrenergic receptor blocking agentCreatine kinase MBDipeptidyl carboxypeptidase inhibitorHydroxymethylglutaryl coenzyme A reductase inhibitorMyoglobinTroponin TCreatine kinaseTroponinAdultAgedArticleBlood samplingClinical trialControlled clinical trialControlled studyCoronary artery blood flowCoronary artery bypass graftCcoronary artery obstructionCreatine kinase blood levelFemaleFollow upHeart muscle ischemiaHeart protectionHumanIntermethod comparisonMajor clinical studyMaleMulticenter studyOff pump coronary surgeryProspective studyRandomized controlled trialRisk reductionTurkey (republic)University hospitalBloodComparative studyCoronary blood vesselMethodologyMiddle aged