Güneş, AygülSığırlı, DenizErcan, İlkerTuran Özdemir, SenemDurmuş, YavuzYıldiz, Tekin2024-06-282024-06-282021-09-281520-9512https://doi.org/10.1007/s11325-021-02502-0https://link.springer.com/article/10.1007/s11325-021-02502-0https://hdl.handle.net/11452/42602Background The aim of this study was to examine whether or not there was a difference in corpus callosum shape between patients with mild to moderate and severe obstructive sleep apnea (OSA) compared with patients who have simple snoring.Methods The landmark coordinate data was obtained from the mid-sagittal magnetic resonance imaging (MRI) images of 70 patients who underwent polysomnography. For comparisons, mild and moderate OSA groups were combined and analyses were performed on three groups; simple snoring/control group, mild or moderate OSA group, and severe OSA group.Results The corpus callosum shape of controls was significantly different from that of the severe OSA group. The most prominent deformities were observed in the genu and rostral body of the corpus callosum for the patients with severe OSA. No significant difference was found between mild/moderate OSA group and simple snoring group in terms of global corpus callosum shape.Conclusion The data demonstrated that severe OSA patients have structural changes in the corpus callosum and deformities may vary as the severity of disease changes.eninfo:eu-repo/semantics/openAccessWhite-matter integrityBody-mass indexPremotor cortexMemoryObstructive sleep apneaCorpus callosumMagnetic resonance imagingStatistical shape analysisNeurosciences & neurologyRespiratory systemArticle0007088179000011201120726310.1007/s11325-021-02502-01522-1709