Atahan, İ. L.Yıldız, FiruzanCengiz, M.Kaplan, B.Özkan, M.Haydaroğlu, A.Şengöz, M.Korçum, A. F.Akmansu, M.2023-10-172023-10-172006-10Atahan, İ. L. vd. (2006). ''Zoledronic acid with either standard or reduced dose palliative radiotherapy in the management of the breast cancer patients with bone metastases: A phase IV randomized study.''. Radiotherapy and Oncology, 81(Supplement 1), S150-S151.0167-8140https://link.springer.com/article/10.1007/s00520-009-0663-xhttp://hdl.handle.net/11452/34385Bu çalışma, 08-12 Ekim 2006 tarihleri arasında Leibzig[Almanya]’da düzenlenen 25. Congress of the European-Society-for-Therapeutic-Radiology-and-Oncology’da bildiri olarak sunulmuştur.Introduction In this prospective study, the efficacy and safety of radiotherapy combined with zoledronic acid was evaluated. Materials and methods Breast cancer patients with painful bone metastases were randomized to either high- or reduced-dose radiotherapy. All patients received zoledronic acid (4 mg) every 28 days from the beginning of radiotherapy. Analgesic and pain scores in addition to visual analog score (VAS) for treatment satisfaction and whole-body bone scintigraphy were evaluated.Results and conclusion No significant differences could be found in analgesic or pain scores and bone scintigraphy results between the groups. Our results suggest that reduced-dose radiotherapy produces similar response rates and response durations when used concomitantly with zoledronic acideninfo:eu-repo/semantics/closedAccessOncologyRadiology, nuclear medicine & medical imagingMeeting Abstract000242719100381S150S15181Supplement 1OncologyRadiology, nuclear medicine & medical imaging