Usta, MehmetAyar, YavuzGöksel, GültekinKaragöz, İsminur Saka2023-02-022023-02-022020-01-20Usta, M. vd. (2020). "Effect of omega-3 polyunsaturated fatty acid supplementation on glycemic control and renal function in type 2 diabetic patients with chronic kidney disease". Acta Medica Mediterranea, 36(2), 821-828.0393-63842283-9720https://doi.org/10.19193/0393-6384_2020_2_128https://www.actamedicamediterranea.com/archive/2020/medica-2/effect-of-omega-3-polyunsaturated-fatty-acid-supplementation-on-glycemic-control-and-renal-function-in-type-2-diabetic-patients-with-chronic-kidney-diseasehttp://hdl.handle.net/11452/30789Introduction: The aim of this study was to evaluate the short-term effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) supplementation on glycemic control and renal function in type 2 diabetic patients with chronic kidney disease. Materials and methods: Twenty-five diabetic patients received medication containing 2 g/day n-3 PUFA orally in addition to standard treatments. Their estimated glomerular filtration rates (eGFR) were <80 mL/min/1.73 m(2). Biochemical values were evaluated before and 3 months after treatment. Results: After three months of supplementation, the changes in serum creatinine, uric acid, eGFR and urinary albumin excretion levels did not reach statistical significance. There was no difference between serum glucose, HbAlC and lipid profile values before and after the n-3 PUFA.supplementation in patients. Only serum albumin significantly increased from 4.10 +/- 0.26 to 4.28 +/- 0.31 g/dL (p=0.016), and systolic blood pressure decreased from 121.4 +/- 14.5 to 116 .6 +/- 14.9 mmHg (p=0.001). Conclusion: Short-term n-3 PUFA supplementation did not affect renal function and glycemic control in patients with type 2 diabetes with chronic kidney disease.eninfo:eu-repo/semantics/openAccessType 2 diabetes mellitusChronic kidney diseaseCardiovascular diseaseOmega-3 polyunsaturated fatty acidsProteinuriaRenal functionBlood-pressureOmega-3-fatty-acid supplementationCardiovascular-diseaseInsulin-resistanceIga nephropathyFish-oilInflammationBiomarkersTrialGeneral & internal medicineArticle0005261216000132-s2.0-85083360934821828362Medicine, general & internalCardiovascular Disease; Omega 3 Fatty Acid; Fish OilsAlbuminCreatinineGlucoseHemoglobin A1cOmega 3 fatty acidUric acidArticleChronic kidney failureClinical articleCreatinine blood levelEstimated glomerular filtration rateFemaleGlucose blood levelGlycemic controlHumanKidney functionLipid fingerprintingMaleNon insulin dependent diabetes mellitusSystolic blood pressureUric acid blood levelUrinary excretion