Karlıbel, İlknur AykurtDulger, SeyhanAksoy, Meliha KasapoğluGüzelsoy, MuhammetTürkoğlu, Ali RızaYıldız, Tekin2023-10-182023-10-182019-04-03Karlıbel, İ. A. vd. (2019). "Effect of cigarette smoking on sexual functions, psychological factors, and disease activity in male patients with ankylosing spondylitis". Aging Male, 22(2), 109-115.1368-55381473-0790https://doi.org/10.1080/13685538.2018.1477935https://www.tandfonline.com/doi/full/10.1080/13685538.2018.1477935http://hdl.handle.net/11452/34422Objective: This study aims to investigate the effect of smoking on sexual functions in AS patients. Patients and methods: A total of 67 male AS patients with a median age of 34 years (range: 18-57) reporting sexual activity at least for the past 4 weeks period were included. Patients were divided into smokers (Group 1, n = 47) and non-smokers (Group 2, n = 20). Fagerstrom test for nicotine dependence, smoking history, exhaled carbon monoxide test were recorded for smoking AS patients. Visual analogue scale (VAS), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis Quality of Life (ASQoL), International Index of Erectile Function (IIEF), Beck Depression Inventory (BDI) were filled for both groups. Results: There was no significant difference between smokers and non-smokers in all evaluation parameters. BASMI scores were significantly lower in the mild dependency subgroup as compared to those with moderate or severe dependency (p = .005 and p = .007, respectively). Total IIEF score and IIEF categories correlated significantly with BASDAI, BASFI, BASMI, ASQoL, pain, fatigue, and cumulative smoking. BDI showed an inverse correlation with the IIEF score and IIEF category (p < .001 r = -0.520, p < .001 r = -0.508, respectively). Conclusions: Sexual function in AS patients is associated with the pain, fatigue, disease activity, functional status, quality of life, depression as well as the cumulative exposure to smoking, and that sexual functions tend to decline with increasing degree of cigarette dependency.eninfo:eu-repo/semantics/closedAccessAnkylosing spondylitisErectile dysfunctionNicotine dependenceSexual dysfunctionSmokingQuality-of-lifeErectile dysfunctionAxial spondyloarthritisElderly-menImpactBathVariablesIndexEndocrinology & metabolismUrology & NephrologyAdultCase-control studiesCigarette smokingHumansMaleMiddle agedPhysical functional performanceProspective studiesSexual dysfunctionPhysiologicalSpondylitisAnkylosingTobacco use disorderArticle0004678447000042-s2.0-8504800469410911522229863428Endocrinology & metabolismUrology & nephrologyAnkylosing Spondylitis; Tragus; ExerciseCarbon monoxideDisease modifying antirheumatic drugNonsteroid antiinflammatory agentTumor necrosis factorAdultAnkylosing spondylitisArticleBath ankylosing spondylitis disease activity indexBath ankylosing spondylitis functional indexBath ankylosing spondylitis metrology indexBeck depression inventoryCigarette smokingControlled studyDepressionDisease activityDisease durationFagerstrom test for nicotine dependenceFatigueFunctional statusHumanInternational index of erectile functionMajor clinical studyMaleMiddle agedMusculoskeletal disease assessmentPainPriority journalPsychological aspectQuality of lifeSexual behaviorSexual functionVisual analog scaleYoung adultAdverse eventAnkylosing spondylitisCase control studyCigarette smokingComplicationPathophysiologyProspective studySexual dysfunctionTobacco dependence