Arslan, SonayEkinci, Ahmet ŞiyarEşbah, OnurUslu, NuriKekilli, Kezban Esra2024-02-192024-02-192014Demiröz, A. C. vd. (2014). "Role of PET/CT in treatment planning for head and neck cancer patients undergoing definitive radiotherapy". Asian Pacific Journal of Cancer Prevention, 15(24), 10899-10903.1513-7368https://doi.org/10.7314/APJCP.2014.15.24.10899http://koreascience.or.kr/article/JAKO201506234294244.pagehttps://hdl.handle.net/11452/39826Background: In this study, we aimed to investigate the benefits of 18F-deoxyglucose positron emission tomography/computed tomography (FGD-PET/CT) imaging for staging and radiotherapy planning in patients with head and neck cancer undergoing definitive radiotherapy. Materials and Methods: Thirty-seven head and neck cancer patients who had undergone definitive radiotherapy and PET/CT at the Uludag University Medical Faculty Department of Radiation Oncology were investigated in order to determine the role of PET/CT in staging and radiotherapy planning. Results: The median age of this patient group of 32 males and 5 females was 57 years (13-84years). The stage remained the same in 18 cases, decreased in 5 cases and increased in 14 cases with PET/CT imaging. Total gross tumor volume (GTV) determined by CT (GTVCT-Total) was increased in 32 cases (86.5%) when compared to total GTV determined by PET/CT (GTVPET/CT-Total). The GTV of the primary tumor determined by PET/CT (GTVPET/CT) was larger in 3 cases and smaller in 34 cases compared to that determined by CT (GTVCT). The GTV of lymph nodes determined by PET/CT (GTVLNPET/CT) was larger in 20 cases (54%) and smaller in 12 cases (32.5%) when compared to GTV values determined by CT (GTVLNCT). No pathological lymph nodes were observed in the remaining five cases with both CT and PET/CT. Conclusions: We can conclude that PET/CT can significantly affect both pretreatment staging and assessed target tumor volume in patients with head and neck cancer. We therefore recommend examining such cases with PEC/CT before treatment.eninfo:eu-repo/semantics/openAccessHead and neck cancerRadiotherapyPET-CTPositron-emission-tomographyFdg-pet/ctMetastasesTumor volumeCtDelineationImpactOncologyAdolescentAdultAgedAged, 80 and overFemaleFluorodeoxyglucose f18Follow-up studiesHead and neck neoplasmsHumansMaleMiddle agedNeoplasm stagingPositron-emission tomographyPrognosisRadiopharmaceuticalsRadiotherapy planning, computer-assistedRadiotherapy, conformalRetrospective studiesTomography, x-ray computedTumor burdenYoung adultArticle0003510589000602-s2.0-849230257251089910903152425605198OncologyPositron Emission Tomography Computed Tomography; Head And Neck Neoplasms; Neck DissectionAdolescentAdultAgedCancer stagingComputer assisted radiotherapyComputer assisted tomographyDiagnostic useFemaleFollow upHead and neck neoplasmsHumanMaleMiddle agedPathologyPositron emission tomographyProceduresPrognosisRetrospective studyScintiscanningTumor volumeVery elderlyYoung adultFluorodeoxyglucose f 18Radiopharmaceutical agent