2022-10-142022-10-142013-06Alper, Z. vd. (2013). "Diagnosis of acute tonsillopharyngitis in primary care: A new approach for low-resource settings". Journal of Chemotherapy, 25(3), 148-155.1120-009X1973-9478https://doi.org/10.1179/1973947813Y.0000000071https://www.tandfonline.com/doi/full/10.1179/1973947813Y.0000000071http://hdl.handle.net/11452/29098Background: Diagnosing GABHS (Group A-beta Hemolytic Streptococcus) tonsillopharyngitis by clinical scoring is a recommended approach in developed countries, but there is still much controversy for low resource settings. Aim: We aimed to assess the impact of Centor criteria with the support of practical laboratory tests. Methods: We prospectively included patients complaining sore throat (N=5282). We evaluated them in terms of Centor scoring and performed white blood cell count (WBC), C-reactive protein (CRP), rapid antigen detecting test, and throat culture. Results: In GABHS cases (n=532, 11.3%), two of the criteria were observed to be positive in more than half of the cases (n=519, 59.3%), while 13 (40.7%) cases met three/four criteria. The specificity of having two criteria was found to be 65.5% and increased to 91.5% after including CRP and WBC. Conclusion: Centor criteria could be safely used to reduce unnecessary antibiotic usage for tonsillopharyngitis in developing countries.eninfo:eu-repo/semantics/closedAccessOncologyInfectious diseasesPathologyPharmacology & pharmacyAcute tonsillopharyngitisCentor scoringCRPPrimary careRapid antigen detecting testWBCAntigen-detection testStreptococcal pharyngitisAntibiotic useSore throatManagementStrepValidationGuidelinesAdultsPredictionAdolescentAdultAgedAged, 80 and overBacterial typing techniquesBiological markersC-reactive proteinChildCost controlDeveloping countriesFemaleHumansInappropriate prescribingLeukocyte countMaleMiddle agedPharyngitisPhysical examinationPrimary health careSensitivity and specificityStreptococcal infectionsStreptococcus pyogenesTurkeyYoung adultArticle0003195004000032-s2.0-8487819025414815525323783139OncologyInfectious diseasesPathologyPharmacology & pharmacySore Throat; Tonsillitis; StreptococcusAmoxicillinC reactive proteinErythromycinPenicillin VAdolescentAntigen detectionArticleChildDiagnostic test accuracy studyFemaleHumanLeukocyte countLeukocyte countMajor clinical studyMalePharyngitisPredictive valuePreschool childPrimary medical careProspective studyQuestionnaireReceiver operating characteristicSchool childSensitivity and specificitySore throatStreptococcus group AThroat cultureTonsillopharyngitis