2022-06-282022-06-282010-03Aydın, U. vd. (2010). "Vacuum-assisted closure therapy in newborn gangrene". Journal of Plastic, Reconstructive and Aesthetic Surgery, 63(3), E277-E279.1748-6815https://doi.org/10.1016/j.bjps.2009.05.049https://www.sciencedirect.com/science/article/pii/S1748681509004380http://hdl.handle.net/11452/27421Gangrene of the newborn or neonatal gangrene is very uncommon, and it usually involves the extremities. Neonatal gangrene seems to be more frequent in pregnancies re-leated with spontaneus rupture of the amniotic sac leading to delayed delivery or dry labour. However, in most of the cases, no aetiological factor can be found. Foetal pressure necrosis and amniotic band sequence are two of the most common causes of this condition. Thrombosis, emboli, congenital heart disease, coagulopathy, sepsis and polycythaemia are some of the other aetiologic factors. Treatment of this condition is usually conservative and supportive. Conservative treatment includes adequate hydration, prevention from infections and allowing the involved area to demarcate in an aseptic environment. In some cases, surgical debridement and further reconstruction can be necessary. In order to prepare the wound bed for surgical closure after surgical debridement, vacuum-assisted closure (VAC) therapy can be a new, highly effective method in the treatment of newborn gangrene. In this article, a case of a neonatal gangrene treated with the application of VAC therapy is presented.eninfo:eu-repo/semantics/closedAccessNewbornGangreneVacuum-assisted closure therapySurgeryForearmGangreneHumansInfant, newbornInfant, newborn, diseasesNegative-pressure wound therapySkin transplantationArticle0002742027000462-s2.0-7514916002127727963319581134SurgeryHeart Catheterization; Blood Vessel Injury; Compartment SyndromesArticleAvascular necrosisCase reportDebridementGangreneHand edemaHumanNewbornNewborn gangrenePrematurityPriority journalSkin graftVacuum assisted closureVaginal delivery