2024-10-012024-10-012006-11-011300-0659https://hdl.handle.net/11452/45551Discoid lupus erythematosus is a chronic, autoimmune disease of the skin. Localized OLE involving the eyelid is seen rarely. In this report, a 28 year-old male who had a localized OLE involving the eyelid has been presented. The examination findings of the patient were a welldefined, slight elevated erythema through the right lower eyelid, scaling on the lesion and madarosis. The diagnosis was made by observing the typical histopatological changes such as hyperkeratosis, lymphoid infiltration at the dermoepidermal junction and telangiectasis in the substantia propria. The eyelid lesion totally disappeared with the treatment of 3 months-systemic hydorxychloroquine (200 mg/day). However, it recurred in the same region 14 months later. Discoid lupus did not recur after the second-systemic hydorxychloroquine treatment. Systemic lupus erythematosus did not develope in the patient followed-up for 40 months.enDiscoid lupus erythematosusEyelidScience & technologyLife sciences & biomedicineOphthalmologyArticle000217221300013512515366