2023-03-272023-03-272019-01-10Ceylan, D. vd. (2019). ''Evaluation of anxiety and depression scales and quality of LIFE in cervical dystonia patients on botulinum toxin therapy and their relatives''. Neurological Sciences, 40(4), 725-7311590-18741590-3478https://doi.org/10.1007/s10072-019-3719-9https://link.springer.com/article/10.1007/s10072-019-3719-9http://hdl.handle.net/11452/31745Objective In this study, quality of life and psychiatric comorbid disorders were investigated in patients with cervical dystonia and their spouses and we also investigated the effect of botulinum toxin (BTX) treatment on these parameters. Material and method Thirty patients with cervical dystonia (CD) on BTX treatment and their spouses (n=30) were included. Beck Depression Scale (BDS), State-Trait Anxiety Inventory I and II (STAI-I, STAI-II), Hospital Anxiety Scale (HAS), Hospital Depression Scale (HDS) for psychiatric comorbid disease assessment, Toronto Western Spasmodic Torticollis Scale (TWSTRS) for disease activity assessment, and Craniocervical Dystonia Questionnaire (CDQ-24), Cervical Dystonia Impact Profile (CDIP-58), and Short Form 36 (SF-36) questionnaires for quality of life assessment were used. BDS, STAI-I and STAI-II, HAS, HDS, and SF-36 scales were also obtained from the spouses. The same tests were applied both before and 8weeks after the BTX treatment. Conclusion In our study, an increase in psychiatric comorbid disorders such as depression and anxiety was observed and the quality of life was adversely affected in all areas in patients. In the spouses of the patients, the rates of psychiatric comorbid disorders such as depression and anxiety were found to be increased when compared to healthy subjects while vitality, mental health, and general health perception were found to be negatively affected. Patients showed improvements in anxiety level, disease activity, and overall quality of life scales after BTX treatment.eninfo:eu-repo/semantics/closedAccessNeurosciences & neurologyCervical dystoniaBotulinum toxin therapyQuality of lifeDepressionAnxietyImpactCareAdultAgedAnxietyAnxiety disordersBotulinum toxinsDepressionDepressive disorderFemaleHumansMaleMiddle agedNeuromuscular agentsQuality of lifeSpousesTorticollisTreatment outcomeYoung adultArticle0004647667000082-s2.0-8506021732872573140430659417Clinical neurologyNeurosciencesInjection; Botulina Toxin A; IncobotulinumtoxinaBotulinum toxinMuscle relaxant agentAdultAgeAgedAnxiety assessmentAnxiety disorderArticleBeck depression inventoryCervical dystoniaCervical dystonia impact profileClinical articleComorbidityCraniocervical dystonia questionnaireDepressionDepression assessmentDisabilityDisease activityEmotionalityFemaleHospital anxiety scaleHospital depression scaleHumanMaleMental healthQuality of lifeSex differenceShort form 36Social supportSpouseState trait anxiety inventoryAnxietyAnxiety disorderDepressionMiddle agedPathophysiologyPsychologyQuality of lifeTorticollisTreatment outcomeYoung adult