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Title: Painful penile ulceration in a patient with malignant atrophic papulosis
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Gastroenteroloji Anabilim Dalı.
Aydoğan, Kenan
Alkan, Gülçin
Koran, S. Karadoğan
Adım, Şaduman Balaban
Kıyıcı, Murat
Tokgöz, Necdet
Keywords: Dermatology
Degos' disease
Malign atrophic papulosis
Penile ulceration
Porcelain-white scars
Cutaneous degos-disease
Issue Date: Sep-2005
Publisher: Wiley
Citation: Aydoğan, K. vd. (2005). "Painful penile ulceration in a patient with malignant atrophic papulosis". Journal of the European Academy of Dermatology and Venereology, 19(5), 612-616.
Abstract: Malignant atrophic papulosis (MAP) is a rare, obliterating vasculopathy affecting multiple systems, frequently with a poor prognosis. Although cutaneous lesions are often the initial presentation, systemic involvement is also common, usually with a fatal outcome. Involvement of the genitalia is very rare. We describe a 45-year-old male patient with multisytemic manifestation of MAP accompanied by painful penile ulceration. The pathogenesis of MAP is not yet fully understood and effective treatment choices are limited. In our case, the combination of pentoxifylline and dipyridamole failed to provide a beneficial effect on the progression of the disease and the patient died due to intestinal and intrathoracic manifestation of MAP. In the present case, attention should be drawn to the following clinical course and therapeutic properties: (i) we describe the second patient in the literature diagnosed with MAP and painful penile ulceration; (ii) to our knowledge, this is the first reported case with oesophageal fistula due to MAP; (iii) we could not confirm the efficacy of pentoxifylline, the recently reported treatment modality, in our patient.
ISSN: 0926-9959
Appears in Collections:Scopus
Web of Science

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