Clinical, ultrasonography and haematology of aglepristone-induced mid-gestation pregnancy terminations in rabbits
dc.contributor.buuauthor | Özalp, Gözde Rabia | |
dc.contributor.buuauthor | Temizel, Ethem Mutlu | |
dc.contributor.buuauthor | Batmaz, Elçin Özocak | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Cerrahi Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Bölümü. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Dahiliye Bölümü. | tr_TR |
dc.contributor.orcid | 0000-0003-4694-6937 | tr_TR |
dc.contributor.researcherid | AAE-3607-2019 | |
dc.contributor.researcherid | ECV-4083-2022 | |
dc.contributor.researcherid | FOM-0178-2022 | |
dc.contributor.scopusid | 23985710500 | tr_TR |
dc.contributor.scopusid | 26430270100 | tr_TR |
dc.contributor.scopusid | 55387315900 | tr_TR |
dc.date.accessioned | 2024-04-01T13:20:39Z | |
dc.date.available | 2024-04-01T13:20:39Z | |
dc.date.issued | 2013 | |
dc.description.abstract | Aglepristone is a safe abortifacient in cats, dogs and rabbits. Although no serious side effects have been reported, there is no information available about the effects of the medicine on haematological parameters. For the first time clinical and ultrasonographic features and haematological profiles were evaluated in rabbits treated with aglepristone 15 and 16 days after mating. Ten healthy 10-14 month-old New Zealand White female rabbits were mated with fertile bucks and pregnancies were confirmed by ultrasound 15 days later. Of these, 5 does were treated with aglepristone (test group, n = 5) whilst the remaining five (control group, n = 5) were treated with a saline solution (0.9% NaCl). The treatment dose was 10 mg/kg body weight, administered subcutaneously once daily on two consecutive days (day 15 and 16 post mating). Ultrasonographic, clinical and haematological assessments were performed daily. Aglepristone treatment induced embryonic fluid resorptions without foetal death in mid-gestation terminations. Following ultrasonographic and haematological examinations, it was established that aglepristone is a safe abortifacient in rabbits. | en_US |
dc.identifier.citation | Özalp, G. R. (2013). “Clinical, ultrasonography and haematology of aglepristone-induced mid-gestation pregnancy terminations in rabbits”. Journal of the South African Veterinary Association, 84(1). | en_US |
dc.identifier.doi | https://doi.org/10.4102/jsava.v84i1.998 | |
dc.identifier.issn | 0038-2809 | |
dc.identifier.issn | 2224-9435 | |
dc.identifier.issue | 1 | tr_TR |
dc.identifier.pubmed | 23718772 | tr_TR |
dc.identifier.scopus | 2-s2.0-84892449789 | tr_TR |
dc.identifier.uri | https://hdl.handle.net/11452/40895 | |
dc.identifier.volume | 84 | tr_TR |
dc.identifier.wos | 000327934500047 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | South African Veterinary Association | en_US |
dc.relation.journal | Journal of the South African Veterinary Association | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Veterinary sciences | en_US |
dc.subject | Progesteron antagonist aglepristone | en_US |
dc.subject | Receptor antagonist | en_US |
dc.subject | Bitches | en_US |
dc.subject.emtree | Aglepristone | en_US |
dc.subject.emtree | Abortive agent | en_US |
dc.subject.emtree | Aglepristone | en_US |
dc.subject.emtree | Estrane derivative | en_US |
dc.subject.emtree | Abortive agent | en_US |
dc.subject.emtree | Estrane derivative | en_US |
dc.subject.emtree | Animal experiment | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Blood analysis | en_US |
dc.subject.emtree | Clinical examination | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Drug safety | en_US |
dc.subject.emtree | Echography | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Mating | en_US |
dc.subject.emtree | Nonhuman | en_US |
dc.subject.emtree | Pregnancy | en_US |
dc.subject.emtree | Pregnancy termination | en_US |
dc.subject.emtree | Rabbit | en_US |
dc.subject.emtree | Animal | en_US |
dc.subject.emtree | Breeding | en_US |
dc.subject.emtree | Chemically induced | en_US |
dc.subject.emtree | Clinical trial | en_US |
dc.subject.emtree | Drug effects | en_US |
dc.subject.emtree | Veterinary abortion | en_US |
dc.subject.emtree | Chemically induced disorder | en_US |
dc.subject.emtree | Drug effect | en_US |
dc.subject.emtree | Veterinary abortion | en_US |
dc.subject.mesh | Abortifacient agents | en_US |
dc.subject.mesh | Abortion, veterinary | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Estrenes | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Pregnancy | en_US |
dc.subject.mesh | Pregnancy, animal | en_US |
dc.subject.mesh | Rabbits | en_US |
dc.subject.scopus | Pyometra; Dog; Deslorelin | en_US |
dc.subject.wos | Veterinary sciences | en_US |
dc.title | Clinical, ultrasonography and haematology of aglepristone-induced mid-gestation pregnancy terminations in rabbits | en_US |
dc.type | Article | en_US |