Comparison of pre-and postpartum serum leptin, ghrelin, and lipid levels in sheep
dc.contributor.buuauthor | Temizel, Ethem Mutlu | |
dc.contributor.buuauthor | Cihan, Hüseyin | |
dc.contributor.buuauthor | Levent, Pınar | |
dc.contributor.buuauthor | Sarıl, Ahmet | |
dc.contributor.buuauthor | Özarda, Yeşim | |
dc.contributor.buuauthor | Yılmaz, Zeki | |
dc.contributor.department | Uludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Veteriner Fakültesi/Biyokimya Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0001-9836-0749 | tr_TR |
dc.contributor.orcid | 0000-0003-1544-6438 | tr_TR |
dc.contributor.researcherid | A-9637-2008 | tr_TR |
dc.contributor.researcherid | AAL-8873-2021 | tr_TR |
dc.contributor.researcherid | T-4585-2019 | tr_TR |
dc.contributor.researcherid | ABH-3742-2020 | tr_TR |
dc.contributor.scopusid | 26430270100 | tr_TR |
dc.contributor.scopusid | 6602381681 | tr_TR |
dc.contributor.scopusid | 56690616700 | tr_TR |
dc.contributor.scopusid | 57202390224 | tr_TR |
dc.contributor.scopusid | 35741320500 | tr_TR |
dc.contributor.scopusid | 35944810500 | tr_TR |
dc.date.accessioned | 2024-01-19T05:25:19Z | |
dc.date.available | 2024-01-19T05:25:19Z | |
dc.date.issued | 2018-03-29 | |
dc.description.abstract | Serum leptin and ghrelin play important roles in energy metabolism and inducing appetite during pregnancy and lactation. We investigated the serum levels of leptin and ghrelin and their relationship with the duration of lactation and serum biochemical responses during the prepartum (last week before lambing) and postpartum periods in sheep. They were also evaluated between pregnant and nonpregnant (control ewes) ewes. For these purposes, pregnant (n = 15) and control Awassi ewes (n = 15) that were 2 years of age were used in this study. Blood samples were collected 1 week before the expected date of lambing (baseline) and for 12 weeks after parturitions. Serum leptin, ghrelin, cholesterol, triglyceride, VLDL, LDL, HDL, NEFA, and phospholipid levels were assayed. Leptin and ghrelin levels of the prepartum period in pregnant and control ewes were 4.5 ng/mL and 3.4 ng/mL (P < 0.05) and 75 pg/mL and 166 pg/ mL (P < 0.01), respectively. The baseline value of ghrelin (81 pg/mL) decreased to 43 pg/mL within 1 week after parturition (P < 0.01). Serum ghrelin levels increased after 1 week. There was also a significant difference in serum ghrelin levels between control ewes and those a week before parturition in pregnant ewes (P < 0.001). The NEFA level was higher in pregnant than in control sheep (P < 0.001). In conclusion, leptin levels tended to decrease during the lactation period, which could be associated with a negative energy balance. Additionally, ghrelin levels tended to gradually increase during lactation to adapt to a negative energy balance. We think that variations in serum leptin and ghrelin might be used to monitor metabolic adaptation during lactation. | en_US |
dc.identifier.citation | Temizel, E. M. vd. (2018). ''Comparison of pre-and postpartum serum leptin, ghrelin, and lipid levels in sheep''. Turkish Journal of Veterinary and Animal Sciences, 42(3), 177-183. | en_US |
dc.identifier.doi | https://doi.org/10.3906/vet-1705-87 | en_US |
dc.identifier.endpage | 183 | tr_TR |
dc.identifier.issn | 1300-0128 | |
dc.identifier.issue | 3 | tr_TR |
dc.identifier.scopus | 2-s2.0-85048198803 | tr_TR |
dc.identifier.startpage | 177 | tr_TR |
dc.identifier.uri | https://journals.tubitak.gov.tr/veterinary/vol42/iss3/5/ | en_US |
dc.identifier.uri | https://hdl.handle.net/11452/39164 | en_US |
dc.identifier.volume | 42 | tr_TR |
dc.identifier.wos | 000435033300005 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Bilimsel ve Teknolojik Araştırma Kurumu | tr_TR |
dc.relation.bap | V-2003/86 | tr_TR |
dc.relation.journal | Turkish Journal of Veterinary and Animal Sciences | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Veterinary sciences | en_US |
dc.subject | Leptin | en_US |
dc.subject | Ghrelin | en_US |
dc.subject | Parturition | en_US |
dc.subject | Energy balance | en_US |
dc.subject | Sheep | en_US |
dc.subject | Dairy-cows | en_US |
dc.subject | Plasma leptinphos | en_US |
dc.subject | Pholipid-metabolism | en_US |
dc.subject | Energy-balance | en_US |
dc.subject | Food-intake | en_US |
dc.subject | Pregnancy | en_US |
dc.subject | Lactation | en_US |
dc.subject | Hormone | en_US |
dc.subject | Ewes | en_US |
dc.subject | Adiposity | en_US |
dc.subject.emtree | Fatty acid | en_US |
dc.subject.emtree | Ghrelin | en_US |
dc.subject.emtree | High density lipoprotein cholesterol | en_US |
dc.subject.emtree | Leptin | en_US |
dc.subject.emtree | Low density lipoprotein cholesterol | en_US |
dc.subject.emtree | Phospholipid | en_US |
dc.subject.emtree | Triacylglycerol | en_US |
dc.subject.emtree | Very low density lipoprotein cholesterol | en_US |
dc.subject.emtree | Animal experiment | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Blood sampling | en_US |
dc.subject.emtree | Calorimetry | en_US |
dc.subject.emtree | Cholesterol blood level | en_US |
dc.subject.emtree | Comparative study | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Energy balance | en_US |
dc.subject.emtree | Ewe | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Lactation | en_US |
dc.subject.emtree | Lipid level | en_US |
dc.subject.emtree | Nonhuman | en_US |
dc.subject.emtree | Pregnancy | en_US |
dc.subject.emtree | Prenatal period | en_US |
dc.subject.emtree | Protein blood level | en_US |
dc.subject.emtree | Puerperium | en_US |
dc.subject.emtree | Radioimmunoassay | en_US |
dc.subject.scopus | Ghrelin Receptors; Acyltransferases; Eating | en_US |
dc.subject.wos | Veterinary sciences | en_US |
dc.title | Comparison of pre-and postpartum serum leptin, ghrelin, and lipid levels in sheep | en_US |
dc.type | Article | en_US |
dc.wos.quartile | Q3 (Veterinary sciences) | en_US |