Diabetik ketoasidozda küçük doz intramüsküler insülin tedavisi sonuçlarının araştırılması
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Date
1987
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Publisher
Uludağ Üniversitesi
Abstract
Diyabetik ketoasidoz tedavisinde, yeni bir yöntem olarak uygulanmaya başlayan küçük doz intramüsküler insülin tedavisiyle alınan sonuçlar araştırıldı . Glisemi düzeyleri 495.3 + 142.1 mg/dl olan 15 olgu çalışmaya alındı. Başlangıç dozu olarak 8 ü. i.v., 8 ü. i.m., tota/16 ü. daha sonra ise 8 ü/saat i. m. kristalize insülin uygulandı. Olgulara ilk 6 saatte toplam 53.7 + 15.8 ü kristalize insülin uygulandı. İlk 2 saatte glisemi değerleri lamlı bir düşüş gösterdi, glisemi düşme hızı saatte 62.2 mg/dl bulundu. Hipoglisemi ve şiddetli hipopotasemi görülmedi.
A new regimen was described for the treatment of diabetic ketoacidosis using small intramuscular doses of insulin. In fifteen patients admitted with plasma-glucose concentrations of 495.3 + 142.1 mg/dl. respectively, a mean initial dose of 16 + 2 units (8 units i.v., 8 units i. m.) was given with hourly doses of 8 units thereafter. Cumulative insulin therapy amounted to 53.7 + 15.8 units at 6 hours. Plasma Glucose level fell significantly within the first two hours of the treatment. Plasma Glucose level fell at a regular rate of 62.2 mg ldl per hour. There was not any complication such as hypoglycemia, severe hypopotassemia.
A new regimen was described for the treatment of diabetic ketoacidosis using small intramuscular doses of insulin. In fifteen patients admitted with plasma-glucose concentrations of 495.3 + 142.1 mg/dl. respectively, a mean initial dose of 16 + 2 units (8 units i.v., 8 units i. m.) was given with hourly doses of 8 units thereafter. Cumulative insulin therapy amounted to 53.7 + 15.8 units at 6 hours. Plasma Glucose level fell significantly within the first two hours of the treatment. Plasma Glucose level fell at a regular rate of 62.2 mg ldl per hour. There was not any complication such as hypoglycemia, severe hypopotassemia.
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Keywords
Diabetik ketoasidoz, Küçük doz intramüsküler insülin tedavisi, Diabetic ketoacidosis, Small dose intramuscular insulin therapy
Citation
Asa, Z. vd. (1987). ''Diabetik ketoasidozda küçük doz intramüsküler insülin tedavisi sonuçlarının araştırılması''. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 14(3), 299-306.