Hiperlipidemik ve normolipidemik kişilerde beta-karoten düzeyi ile serum lipidleri arasandaki ilişkilerin incelenmesi
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Date
1998
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Publisher
Uludağ Üniversitesi
Abstract
Bu çalışma hiperlipidemi ve normolipidemic beta-karotenle serum lipidlerinin ilişkisinin incelenmesi amacıyla üç değişik tip hiperlipidemik ve bir normoipidemik kontrol grubu olmak üzere dört grupta gerçekleştirildi. Bu amaçla tüm olgularda serum beta-karoten. eşitli lipid parametreleri total kolesterol, trigliserid. yüksek dansiteli lipoprotein cholesterol HDL-K). düşük dansiteli lipoprotein-cholesterol LDL-K)j. apolipoprotein B ve A-1 düzeyleri tayin edildi. Çalışmaya 25-50 yaş grubundaki sağlıklı erkekler dahil edildi. Serum beta-karoten düzeyinin hiperkolesterolemik grupta kontrol grubuna göre istatistiksel olarak anlamlı şekilde daha yüksek olduğu bulundu rp<0.05). Normolipidemic kontrol grubunda beta-korotenin HDL-K ile negatif =-0.626). total kolesterol HDL-K oranı ile ise pozitif (r = 0. 711) yönde anlamlı korelasyonlar gösterdiği saptandı. Hipertrigliseridemik ve karışık tip hiperlipidemik gruplarda beta-karoten ile HDL-K arasındaki pozitif korelasyonlar istatistiksel olarak anlamlı olmadığı bulundu. Beta-karoten kontrol grubunda total kolesterol: hiperlipidemik gruplarda ise trigliserid ile ilişkinin göreceli olarak daha yüksek olduğu görüldü.
The aim of the study was to investigate the relationships between beta-carotene and serım lipids. In three different types of hperlpidemic and one normolipidemic control. totally in four groups serum beta-carotene. polipopro in B and A-1. and l'(trious lipid par(letters total cholesterol, triglycerides, high density lipoprotein cholesterol (HDL-C). low density lipoprotein-cho/esterol (LDL-C) were analyzed. Ma/e subjects only aged between 25- 50 ll'ere included info the study. Beta-carotene level was found to be higher in hypercholesterolemic subjects in comparison to the control group fp<0.05). Beta-carotene had a statistically significant negative correlation with HDL-C (r =-0.626) white a positive significant correlation with total cholesterol HDL-C ratio (r = O. 711) in the normolipidemic group. Although there were not positive correlations between beta-carotene and HDL-C in both of the hypertriglyceridemia and mixedıpe perlipid mic groups. they were not tati aly significant. Although there l'ere not significam correlation of beta-carotene with total cholesterol in the control group and triglycerides in hyperlipidemic groups were found to be relatively higher.
The aim of the study was to investigate the relationships between beta-carotene and serım lipids. In three different types of hperlpidemic and one normolipidemic control. totally in four groups serum beta-carotene. polipopro in B and A-1. and l'(trious lipid par(letters total cholesterol, triglycerides, high density lipoprotein cholesterol (HDL-C). low density lipoprotein-cho/esterol (LDL-C) were analyzed. Ma/e subjects only aged between 25- 50 ll'ere included info the study. Beta-carotene level was found to be higher in hypercholesterolemic subjects in comparison to the control group fp<0.05). Beta-carotene had a statistically significant negative correlation with HDL-C (r =-0.626) white a positive significant correlation with total cholesterol HDL-C ratio (r = O. 711) in the normolipidemic group. Although there were not positive correlations between beta-carotene and HDL-C in both of the hypertriglyceridemia and mixedıpe perlipid mic groups. they were not tati aly significant. Although there l'ere not significam correlation of beta-carotene with total cholesterol in the control group and triglycerides in hyperlipidemic groups were found to be relatively higher.
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Keywords
Beta-karoten, Hiperlipidemi, Lipidler, Beta-carotene
Citation
Ulukaya, E. vd. (1998). ''Hiperlipidemik ve normolipidemik kişilerde beta-karoten düzeyi ile serum lipidleri arasandaki ilişkilerin incelenmesi''. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 25(1-2-3), 1-4.