Low dose cyclosporin A treatment in generalized pustular psoriasis
Date
2001
Authors
Çelebi, Solmaz
Karadeniz, Aynur
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley
Abstract
Generalized pustular psoriasis is a rare form of psoriasis, seldom seen in children. Three patients with generalized pustular psoriasis are presented, two of whom were a sister and brother and whose grandfather also had pustular psoriasis. Lesions consisted of pustular, erythematous, scaly, follicular papules located on the trunk, scalp, and extremities. The pustules in some areas coalesced to form lakes. Histologic examination of several biopsy specimens revealed the changes of pustular psoriasis, which were parakeratosis, elongation of the rete ridges, and deep spongioform pustules and Munro abscesses. All patients were treated with cyclosporin A for periods of 2-12 months. The doses ranged from 1 to 2 mg/kg/day. Clearance of psoriatic lesions occurred after 2-4 weeks of therapy.
Description
Keywords
Skin, Childhood, Dermatology, Pediatrics
Citation
Kılıç, S. S. vd. (2001). "Low dose cyclosporin A treatment in generalized pustular psoriasis". Pediatric Dermatology, 18(3), 246-248.