Multidedektör bilgisayarlı tomografi koroner kalsiyum skorlama ile karotis intima-media kalınlığı arasındaki ilişki
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Date
2013-01-21
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Uludağ Üniversitesi
Abstract
Çalışmamızın amacı, sistemik aterosklerozun erken dönem değişikliklerinin bir göstergesi olan karotis intima-media kalınlığı (KİMK) ile multidedektör bilgisayarlı tomografi (MDBT) ile belirlenen koroner kalsiyum skoru ve koroner arter hastalığının varlığı ve yaygınlığı arasındaki ilişkinin araştırılmasıdır. Klinik endikasyonla MDBT koroner anjiografi yapılması planlanan 18-65 yaş arası 100 hasta çalışmaya katıldı. MDBT ile koroner kalsiyum skorları (KKS) belirlendi. Hastaların demografik özellikleri kaydedildi. B-mod ultrason ile her iki ana karotis arterde intima-media kalınlığı ölçüldü ve karotis plak varlığı araştırıldı. Koroner kalsiyum skorlaması ile KKS=0 ve KKS>0 olanlar belirlendi. KKS>0 olanlar da KKS= 0-10, 11-100, 101-400 ve >400 olarak gruplandırıldı. KKS değerlendirildiğinde 56 hastada KKS=0 ve 39 hastada KKS>0 bulundu. KKS grupları arasında KİMK bakımından anlamlı fark bulundu (p<0,001). KKS=0 ve >0 olanlar arasında karotis plak varlığı bakımından anlamlı fark bulundu (p<0,05). Sonuç olarak, ultrasonografi ile KİMK ölçümü, erken dönem aterosklerozun belirlenme sinde ve kardiyovasküler risk değerlendirmesinde kullanılabilecek, invaziv olmayan, kolay uygulanabilir ve ucuz bir tanı yöntemid
The purpose of our study is to investigate the relationship between carotid intima-media thickness (CIMT) -an indicator of systemic athero sclerotic changes in early phases and coronary calcium score- an indicator of coronary artery disease (CAD) measured by multidetector computed tomography (MDCT). 100 patients, aging between 18-65 years, whom had clinical indications for MDCT coronary angiography examination were included in the study. Coronary calcium scores (CCS) were measured by MDCT. Demographic features of patients were recorded. Intima-media thickness of both common carotid arteries was measured, mean CIMT was calculated and presence of carotid plaques were looked for using B-mod ultrasound. CCS:0 and CCS>0 subjects were determined with coronary calcium scoring. CCS>0 subjects were divided into CCS: 0-10, 11-100, 101-400 and >400 groups. CCS of 56 patient was 0 and 39 patient was higher than 0. Statisti cally significant difference between CCS and CIMT was determined (p<0,001). Also significant difference regarding presence of carotid plaques between CCS=0 and >0 groups was observed (p<0,05). In conclusion, CIMT measurement with ultrasonography is a non-invasive, easily performed and cheap diagnostic tool for early detection of atherosclerosis and cardiovascular risk assessment.
The purpose of our study is to investigate the relationship between carotid intima-media thickness (CIMT) -an indicator of systemic athero sclerotic changes in early phases and coronary calcium score- an indicator of coronary artery disease (CAD) measured by multidetector computed tomography (MDCT). 100 patients, aging between 18-65 years, whom had clinical indications for MDCT coronary angiography examination were included in the study. Coronary calcium scores (CCS) were measured by MDCT. Demographic features of patients were recorded. Intima-media thickness of both common carotid arteries was measured, mean CIMT was calculated and presence of carotid plaques were looked for using B-mod ultrasound. CCS:0 and CCS>0 subjects were determined with coronary calcium scoring. CCS>0 subjects were divided into CCS: 0-10, 11-100, 101-400 and >400 groups. CCS of 56 patient was 0 and 39 patient was higher than 0. Statisti cally significant difference between CCS and CIMT was determined (p<0,001). Also significant difference regarding presence of carotid plaques between CCS=0 and >0 groups was observed (p<0,05). In conclusion, CIMT measurement with ultrasonography is a non-invasive, easily performed and cheap diagnostic tool for early detection of atherosclerosis and cardiovascular risk assessment.
Description
TURKRAD 2011 kongresinde sunulmuştur.
Keywords
Ateroskleroz, Karotis intima media, Koroner kalsiyum, MDBT, Ultrasonografi, Atherosclerosis, Carotid intima-media, MDCT, Coronary calcium, Ultrasonography
Citation
Kır, H. İ. vd. (2013). "Multidedektör bilgisayarlı tomografi koroner kalsiyum skorlama ile karotis intima-media kalınlığı arasındaki ilişki". Uludağ Üniversitesi Tıp Fakültesi Dergisi, 39(1), 33-37.