Böbrek biyopsisi ile reaktif amiloidoz tanısı alan hastaların retrospektif analizi
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Date
2012-03-13
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Uludağ Üniversitesi
Abstract
Bu çalışmada böbrek biyopsisi sonucu AA amiloidozu tanısı alan 32 hastanın demografik,klinik ve laboratuar özellikleri retrospektif olarak incelendi. Yaş ortalaması 49,3±14,5, Cinsiyet dağılımı (E/K) 22/10, Biyopsi endikasyonu; 29 (%90,6) olguda nefrotik sendrom, 3 (%3,4) olguda açıklanamayan akut böbrek yetmezliği nedeniyle koyuldu. 14 (%43,8) olguda altta yatan hastalık saptanamadı. 11(%34) olguda romatolojik hastalık, 3 (%9,4) olguda malinite ve 3 (%9,4) olguda kronik bakteriyal enfeksiyon saptandı.1 (%3) olguda biyopsi sonrası kanama gelişti. AA amiloidozu düşünülen hastalarda böbrek biyopsisi güvenle tercih edilebilir. İdyopatik olguların oranı yüksek olup malign hastalıklar etyolojide düşünülmelidir.
In this study, we retrospectively reviewed clinical, laboratory and demographic features of 32 patients who was dignosed by renal biopsy. The mean age of patients and male/female ratio were 49,3±14,5 and 22/10, respectively. The most common indications for renal biopsy were nephrotic sydrome in 29 cases (%90,6), acute renal injury with unknown etiology in 3 cases (%3,4). The number of clinical diagnosis of patients were rheumatologic disease , chronic bacterial infection , and malign disease, 11 (%34) 3(%9,4), 3(%9,4) respectively. 14 (%43,8) pateints were considered as idiopathic cases. Major hematom was observed in 1 (%3) patient. Renal biopsy in renal amyloidosis might be chosen confidently and a malignant disease as an etiological factor should be kept in mind.
In this study, we retrospectively reviewed clinical, laboratory and demographic features of 32 patients who was dignosed by renal biopsy. The mean age of patients and male/female ratio were 49,3±14,5 and 22/10, respectively. The most common indications for renal biopsy were nephrotic sydrome in 29 cases (%90,6), acute renal injury with unknown etiology in 3 cases (%3,4). The number of clinical diagnosis of patients were rheumatologic disease , chronic bacterial infection , and malign disease, 11 (%34) 3(%9,4), 3(%9,4) respectively. 14 (%43,8) pateints were considered as idiopathic cases. Major hematom was observed in 1 (%3) patient. Renal biopsy in renal amyloidosis might be chosen confidently and a malignant disease as an etiological factor should be kept in mind.
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Keywords
AA amloidoz, Biyopsi, Nefrotik sendrom, Malignite, AA amyloidosis, Biopsy, Nephrotic syndrome, Malignancy
Citation
Yıldız, A. vd. (2012). "Böbrek biyopsisi ile reaktif amiloidoz tanısı alan hastaların retrospektif analizi". Uludağ Üniversitesi Tıp Fakültesi Dergisi, 38(2), 63-65.