Güney Marmara Bölgesi hodgkin hastalığının epidemiyolojik özellikleri
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Date
2002-11-01
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Uludağ Üniversitesi
Abstract
Hodgkin Hastalığı’nın ülkeler arasında epidemiyolojik farklılıklar gösterdiği bilinmektedir. Çalışmamızda, Uludağ Üniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı Hematoloji Bilim Dalı’nda 1978-1994 yılları arasında takip ve tedavi edilen toplam 86 Hodgkin Hastalığı olguları, yaş, cinsiyet, histolojik alt grup, evre ve yaşanılan bölge parametrelerine göre epidemiyolojik yönden incelendi. Erkeklerin %57, kadınların %43 oranlarını oluşturdukları, erkek/kadın oranı 1.3, ortalama yaş 38, en küçük yaş 14 ve en büyük yaş 71 olarak saptandı. Adolesan döneminden itibaren insidansın arttığı ve 20-34 yaşları arasında birinci, 55-59 yaşları arasında ikinci pik oluşarak bimodal yaş dağılımının bulunduğu tesbit edildi. Histolojik alt grup dağılımında %61.6 oranıyla mikst sellüler tipin hakim olduğu belirlendi. Ann Arbor Evrelemesine göre olguların %86 oranı ile ileri evrede (%41.8 evre III-B, %44.2 evre IV) müracaat ettikleri saptandı. Serbest meslek sahiplerinin (esnaf) %18.6, işçilerin %10.5, çiftçilerin %16.3, öğrencilerin %5.8, memurların %5.8, ev hanımlarının %43 oranlarını oluşturdukları ve olguların %74.4'nün kentte, %25.6'nın kırsal kesimde yaşadıkları tesbit edildi. Sonuç olarak; Güney Marmara Bölgesi Hodgkin Hastalığı olgularında bimodal yaş dağılımının bulunduğu, mikst sellüler alt grubun hakim olduğu ve olguların ileri evrede (evre III-B ve IV) hastahaneye müracaat ettikleri belirlendi.
It is known that Hodgkin’s Disease has some epidemiological differences among countries. In our study, in Hematology Division of Medical Faculty of Uludağ University Hodgkin's Disease cases that were followed up and treated between the years 1978-1994 were assessed retrospectively according to parameters concerning age, sex, histopathologic subgroup, stage, occupation and region. It was established that of 86 Hodgkin's Disease cases (57% male, 43% female, mean age 38, the lowest age 14, the highest age 76), 61.6% were mixed cellularity. It was also determined that first peak was during 20-34 years of, second peak during 55-59 years of age. In accordance with Ann-Arbor stage classification 86% applied in advance stage (41.8% in stage III-B, 44.2% in stage IV). It was found that the rate of traders was 18.6%, workers 10.5%, farmers 16.3%, students 5.8%, civil servants 5.8%, housewives 43%. 74.4 percent of cases were living in the cities, 25.6% in the rural region. Consequently, we came to the conclusion that Hodgkin's Disease cases in southern Marmara region had bimodal age distribution, mixed cellularity type is predominant and that the cases applied to hospital during advance stages (stage III-B and IV)
It is known that Hodgkin’s Disease has some epidemiological differences among countries. In our study, in Hematology Division of Medical Faculty of Uludağ University Hodgkin's Disease cases that were followed up and treated between the years 1978-1994 were assessed retrospectively according to parameters concerning age, sex, histopathologic subgroup, stage, occupation and region. It was established that of 86 Hodgkin's Disease cases (57% male, 43% female, mean age 38, the lowest age 14, the highest age 76), 61.6% were mixed cellularity. It was also determined that first peak was during 20-34 years of, second peak during 55-59 years of age. In accordance with Ann-Arbor stage classification 86% applied in advance stage (41.8% in stage III-B, 44.2% in stage IV). It was found that the rate of traders was 18.6%, workers 10.5%, farmers 16.3%, students 5.8%, civil servants 5.8%, housewives 43%. 74.4 percent of cases were living in the cities, 25.6% in the rural region. Consequently, we came to the conclusion that Hodgkin's Disease cases in southern Marmara region had bimodal age distribution, mixed cellularity type is predominant and that the cases applied to hospital during advance stages (stage III-B and IV)
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Keywords
Hodgkin hastalığı, Hodgkin’s disease, Epidemiyoloji, Epidemiology
Citation
Ali, R. vd. (2002). "Güney Marmara Bölgesi hodgkin hastalığının epidemiyolojik özellikleri" Uludağ Üniversitesi Tıp Fakültesi Dergisi, 28(2),39-44.