Pulmoner kontüzyonlu köpeklerde klinik, laboratuvar, radyolojik ve bronkoskopik bulguların karşılaştırılması
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Date
2019-12-24
Authors
Çetin, Melike
Journal Title
Journal ISSN
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Publisher
Uludağ Üniversitesi
Abstract
Bu çalışmada pulmoner kontüzyonlu (PK) köpeklerde klinik, laboratuvar, radyolojik ve bronkoskopik bulguların karşılaştırılması amaçlandı. Çalışma materyalini kliniklere getirilen farklı ırk, yaş ve cinsiyette, PK tanısı konmuş toplam 26 adet köpek oluşturdu. Köpeklerin genel muayene, rutin hematolojik, kan gazı analizi, radyolojik ve genel anestezi altında bronkoskopik muayeneleri yapıldı. Bronkoskopi sonrası, sitoloji için bronkoalveolar lavaj (BAL) yapıldı. Tüm elde edilen bulgular kaydedildi. PK’nın radyolojik derecelendirmesine göre olgular grup 1 (n=16) (orta derece) ve grup 2 (n=10) (şiddetli derece) olarak ikiye ayrıldı. Her iki gruptaki olguların genel muayene, hematolojik değerler ile kan gazı analiz parametreleri gruplar arası olarak anlamlılık yönünden Mann Whitney U testi ile istatistiksel olarak analiz edildi. Genel muayenede pulzasyon ve respirasyonda yükselme, mukozal solgunluk, akciğer seslerinde anormallikler; hematolojik muayenede total lökosit ve nötrofilde yükselme, hematokrit ve trombosit değerlerinde düşme; kan gazı analizlerinde belirgin asidemi ve hipoksemi ile karşılaşıldı. Radyolojik olarak alveoler ve intersitisyel desen görünümlerine ilaveten 13 pnömotoraks, 4 plevral efüzyon, 2 kosta kırığı, 1 akciğer atelektazisi ve 1 yelken göğüs (flail chest) tanındı. Trakeobronkoskopide 9 şiddetli, 3 orta ve 7 hafif derecede kanama, 3 solgun ve 8 hiperemik mukoza gözlendi. Sitolojide, farklı olgularda nötrofil artışı, dökülmüş epitel hücresi, eritrosit, mukoprotein iplikler, makrofaj hücreleri, bakteri ve hiposelüler yapı gözlendi. İstatistiksel olarak gruplar arasında genel muayene, rutin hematolojik ve kan gazı analizi bulguları bakımından anlamlı bir farklılık saptanmadı. Sonuç olarak, sunulan çalışmada elde edilen genel muayene, rutin hematolojik ve kan gazı analizleri, radyolojik muayene ile birlikte trakeobronkoskopi ve BAL sıvısı sitolojisinin, PK’lı köpeklerin solunum sisteminin değerlendirilmesinde önemli olduğu görülerek, bu bulguların gerek veteriner pratiğe ve gerekse akademik çalışmalara katkı sağlayacağı kanısına varılmıştır.
The aim of this study was to compare clinical, laboratory, bronchoscopic and radiological findings in dogs with pulmonary contusion (PK). The material of the study consisted of total 26 dogs with different breeds, ages and genders, who were diagnosed with PK. General examination, routine hematologic, blood gas analysis, radiological and bronchoscopic examinations under general anesthesia were performed. After bronchoscopy, bronchoalveolar lavage (BAL) was performed for cytology. All findings were recorded. The patients were divided into two groups according to the radiological grading of PK: group 1 (n=16) (moderate) and group 2 (n=10) (severe). General examination, hematological values and blood gas analysis parameters of the cases in both groups were statistically analyzed by Mann Whitney U test for significance between the groups. Increasing of the pulsation and respiration rates, mucosal pallor, abnormal lung sounds; in the hematological examination, total increased leukocyte and neutrophil values, decreased hematocrit and platelet values; significant acidemia and hypoxemia was encountered in the blood gas analysis. Radiologically, 13 pneumothorax, 4 pleural effusions, 2 rib fractures, 1 lung atelectasis and 1 flail chest were diagnosed as well as alveolar and interstitial pattern appearance. Tracheobronchoscopy revealed 9 severe, 3 moderate and 7 mild bleeding, 3 pale and 8 hyperemic mucosa. Cytology showed increased neutrophils, spilled epithelial cells, erythrocytes, mucoprotein strands, macrophage cells, bacteria and hypocellular structure in different cases. There was no statistically significant difference between the groups in terms of general examination, routine hematological and blood gas analysis findings. As a result, the general examination, routine hematological and blood gas analysis, radiological examination and tracheo-bronchoscopy and BAL fluid cytology obtained in the present study were found to be important in the evaluation of the respiratory system of dogs with PK, and it would be considered that these findings contributed to both veterinary practice and academic studies.
The aim of this study was to compare clinical, laboratory, bronchoscopic and radiological findings in dogs with pulmonary contusion (PK). The material of the study consisted of total 26 dogs with different breeds, ages and genders, who were diagnosed with PK. General examination, routine hematologic, blood gas analysis, radiological and bronchoscopic examinations under general anesthesia were performed. After bronchoscopy, bronchoalveolar lavage (BAL) was performed for cytology. All findings were recorded. The patients were divided into two groups according to the radiological grading of PK: group 1 (n=16) (moderate) and group 2 (n=10) (severe). General examination, hematological values and blood gas analysis parameters of the cases in both groups were statistically analyzed by Mann Whitney U test for significance between the groups. Increasing of the pulsation and respiration rates, mucosal pallor, abnormal lung sounds; in the hematological examination, total increased leukocyte and neutrophil values, decreased hematocrit and platelet values; significant acidemia and hypoxemia was encountered in the blood gas analysis. Radiologically, 13 pneumothorax, 4 pleural effusions, 2 rib fractures, 1 lung atelectasis and 1 flail chest were diagnosed as well as alveolar and interstitial pattern appearance. Tracheobronchoscopy revealed 9 severe, 3 moderate and 7 mild bleeding, 3 pale and 8 hyperemic mucosa. Cytology showed increased neutrophils, spilled epithelial cells, erythrocytes, mucoprotein strands, macrophage cells, bacteria and hypocellular structure in different cases. There was no statistically significant difference between the groups in terms of general examination, routine hematological and blood gas analysis findings. As a result, the general examination, routine hematological and blood gas analysis, radiological examination and tracheo-bronchoscopy and BAL fluid cytology obtained in the present study were found to be important in the evaluation of the respiratory system of dogs with PK, and it would be considered that these findings contributed to both veterinary practice and academic studies.
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Keywords
Pulmoner kontüzyon, Pulmonary contusion, Laboratuvar analizi, Radyoloji, Bronkoskopi, Köpek, Laboratory analysis, Radiology, Bronchoscopy, Dog
Citation
Çetin, M. (2019). Pulmoner kontüzyonlu köpeklerde klinik, laboratuvar, radyolojik ve bronkoskopik bulguların karşılaştırılması. Yayınlanmamış doktora tezi. Uludağ Üniversitesi Sağlık Bilimleri Enstitüsü.