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Permanent URI for this collectionhttps://hdl.handle.net/11452/24864
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Browsing by Department "Anesteziyoloji Ana Bilim Dalı"
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Publication Esmolot pretreatment reduces the frequency and severity of pain on injection of rocuronium(Elsevier Science, 2007-09) Yavaşçaoğlu, Belgin; Kaya, Fatma Nur; Özcan, Berin; Tıp Fakültesi; Anesteziyoloji Ana Bilim Dalı; AAG-9356-2021; AAI-7914-2021; AAI-8213-2021; 6602742300; 7003619647; 6603825848Objective: To determine the effect of esmolol on the frequency and severity of pain and withdrawal reactions after injection of rocuronium and to compare it with lidocaine and placebo. Design: Prospective, randomized, double-blind, placebo-controlled study. Setting: Single university hospital. Patients: 120 ASA physical status I and 11 patients undergoing general anesthesia for elective surgery. Interventions: Patients were randomized to receive esmolol (0.5 mg/kg), lidocaine (0.5 mg/kg), or placebo, followed by a subparalyzing dose of rocuronium. After induction of anesthesia with propofol and fentanyl, an intubating dose of rocuronium 0.6 mg/kg was given. Measurements: Patients were observed after injection of rocuronium 0.05 mg/kg, then immediately asked if they had pain in the arm. The response was assessed; discomfort, pain, and withdrawal of the hand were recorded and graded using a 4-point scale (none, mild, moderate, or severe). After the intubating dose of rocuronium, withdrawal reactions were scored as follows: (a) no pain response, (b) pain limited to the wrist, (c) pain limited to the elbow/shoulder, or (d) generalized pain response. Results: 31 patients (77.5%) in the esmolol group, 32 (80%) in the lidocaine group, and 15 (37.5%) in the placebo group reported no pain (both groups vs placebo, P < 0.001). Moderate pain was seen in only one patient receiving lidocaine, in 6 placebo patients, but in none in the esmolol group (esmolol vs placebo, P < 0.05). Severe pain was felt by 8 patients receiving placebo, but by none receiving esmolol or lidocaine (P < 0.01). Frequency of withdrawal response after rocuronium was 2.5%, 17.5%, and 40% in the esmolol, lidocaine, and placebo groups, respectively (esmolol group vs placebo, P < 0.001; lidocame group vs placebo, P < 0.05). Conclusion: Esmolol, like lidocame, reduces the frequency of pain and withdrawal reaction associated with rocuronium injection.Publication Fatal hydrothorax due to misplacement of a nasoenteric feeding tube(Sage Publications, 2001) Acar, H. Volkan; Kahveci, Ferda; İşçimen, Remzi; Gurbet, Alp; Uysal, Hale Yarkan; Kutlay, Özden; Tıp Fakültesi; Anesteziyoloji Ana Bilim Dalı; AAG-9356-2021; 6602742300; 7007146835; 16645821200; 35618853300; 8290444400; 6602199747Blind nasoenteric intubation was attempted in a patient with chronic parkinsonism. The tube was inadvertently misplaced and penetrated the left pleural cavity. The next day, the patient developed cardiopulmonary arrest during dietary supplement infusion. This complication ultimately led to the patient's death. We have reviewed the known complications of nasoenteric tube placement and conclude that difficult insertion in patients at risk from tube misplacement should be followed by chest radiography to confirm the correct placement of the tube before nutritional support is started.