1988 Cilt 7 Sayı 1-2-3

Permanent URI for this collectionhttps://hdl.handle.net/11452/31984

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Browsing by BUU Author "Kahraman, Mustafa"

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    Farelerde oluşturulan i̇mmunosuppresi̇f etki̇ ile kanlarındaki vitamin A ve Beta-karoten düzeyleri arasındaki ilişkiler üzeri̇nde bir araştırma
    (Uludağ Üniversitesi, 1988) Mert, Nihat; Kahraman, Mustafa; Oğan, Canan; Şeker, Ayşin; Uludağ Üniversitesi/Veteriner Fakültesi/Mikrobiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.
    Eighty white mice were divided equally into 4 groups. Group I unvaccinated controls, Group II vaccinated controls Group III. experimental group receiving 400 mg/lt. nitriate and Group IV. experimental group receiving 400/lt. intriate in drinking water. All mice except the group I were vaccinated with Newcastle disease virus, Hitchner B1 strain subcutaneously. Three times repeatedly every other day. Serum samples for each group of mice were obtained from the blood pooled of each group were examined for the amount of vitamin A and Beta-caroten and for the immunosuppresive effect of nitrite and nitrate on the mice. All of the three parameters were found to be decreased, in groups of mice receivied nitrite and nitrate canpating the other groups. Amounts of Beta-caroten were measured as 5.236 3.336, 1.428 and 0.952 mgr/100 ml. in groups I, ll, III and IV respectively. Vitamin A values were high in group I and II (46.74) and 47.64) and were 28.38 and 21.98 mg/ml in 100 ml/serum in groups III and IV. HI titres were determined as 2-² , 2-⁶ and 2-⁵ and 2-⁴ indicating lower titers in the experimental groups.
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    Nitrat ve nitrit'in immunosuppresif olarak etkilediği farelerde fekal germ sayıları üzerinde bi̇r araştırma
    (Uludağ Üniversitesi, 1988) Kahraman, Mustafa; Çarlı, Tayfun; Tayyar, Mustafa; Uludağ Üniversitesi/Veteriner Fakültesi.
    A month-old, sixty Swiss mice were divided into three equal groups. First group was untreated controls, as the second group received Nitrite (0.4 gr/lt) in their drinking water. The third group being treated with Nitrate (0.4 gr/lt) they were immunosuppressed for ten months. By the end of this ten month treatment period, all three groups were ND vaccinated for three times, a day apart (New Castle Hitchner B1 virus). The vaccine dose was ten times of normal vaccination dosage. Fecal bacterial counts were taken from samples collected at the end of every month for ten times. Fifteen days after the third vaccination, the blood samples were obtained to run the HI tests. The blood samples were pooled for each group and the sera were used to compare the resulting HI values between immunoactive and immunosuppressed animals. The total fecal bacterial counts did not show any variation in the first group, while the immunosuppressed groups (2 and 3) demonstrated a gradual decrease. The HI titers were similarly affected and the immunosuppressed animals showed a gradual declining comparing with the first untreated control group. The HI titer of the first group was 2-⁶ , while nitrite group had a titer of 2-⁵ and the nitrate group had a titer of 2-⁴.
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    Nitrat ve nitrit'in immunosuppresif olarak etkiledikleri farelerde bazı biyolojik değişiklikler üzerinde araştırmalar II. bazı doku ve organlarda gözlenen histopatolojik değişiklikler
    (Uludağ Üniversitesi, 1988) Kahraman, Mustafa; Ertürk, Erdoğan; Özkula, Mihriban; Sönmez, Gürsel; Uludağ Üniversitesi/Veteriner Fakültesi/Mikrobiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Veteriner Fakültesi/Patoloji Anabilim Dalı.
    Eighty Swiss mice divided into 4 equal groupı as follow: Group I Negative controls (nonvaccinated with Newcastle Disease vaccine and did not receive any additional treatment); Group. Il was consisted of 20 mice that received ND vaccine only; Group III had 20 mice that were ND vaccinated and drunk nitrite water (0.4 gr/lt) and the last group IV, had equal number of mice that were immunostimulated with ND vaccination and was additionally treated with nitrate in their drinking water (0.4 gr./lt) for a period of 26 weeks. Three mice randomly selected from each group were used to obtain blood samples and histopathological evaluations by the termination. The respective HI tilers for groups were 2-², 2-⁶, 2-⁵ and 2-⁴.The second group (vaccinated controls) being highest and followed by the third and the fourth groups showed moderate severe to lymphoid hyperplasia in thymus, peripheral lymph nodes and payer patches observed by light microscopy. In some cases, as the result of this severe lymphoid response, some mononuclear cell infiltrations into kidney, liver and even into the lungs were detected. The strength of hyperplasia and resulting infiltrations were in agreement with the immunosuppressive potential of nitrate and nitrite administered in drinking water.
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    Sterilizasyon
    (Uludağ Üniversitesi, 1988) Kahraman, Mustafa; Uludağ Üniversitesi/Veteriner Fakültesi/Mikrobiyoloji Anabilim Dalı.
    Herhangi kullanılacak bir maddenin veya yiyeceğin mikropsuz hale getirilmesine STERİLİZASYON denilir. Bunu dezenfeksiyon ile karıştırmamak gerekir. Dezenfeksiyon bulaşık bir maddenin mikroplarını öldürmek için kimyasal vasıtalarla yapılan işlemdir.