1988 Cilt 7 Sayı 1-2-3

Permanent URI for this collectionhttps://hdl.handle.net/11452/31984

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    Nitrat ve nitrit'in immunosuppresif olarak etkilediği farelerde fekal germ sayıları üzerinde bi̇r araştırma
    (Uludağ Üniversitesi, 1988) Kahraman, Mustafa; Çarlı, Tayfun; Tayyar, Mustafa; Uludağ Üniversitesi/Veteriner Fakültesi.
    A month-old, sixty Swiss mice were divided into three equal groups. First group was untreated controls, as the second group received Nitrite (0.4 gr/lt) in their drinking water. The third group being treated with Nitrate (0.4 gr/lt) they were immunosuppressed for ten months. By the end of this ten month treatment period, all three groups were ND vaccinated for three times, a day apart (New Castle Hitchner B1 virus). The vaccine dose was ten times of normal vaccination dosage. Fecal bacterial counts were taken from samples collected at the end of every month for ten times. Fifteen days after the third vaccination, the blood samples were obtained to run the HI tests. The blood samples were pooled for each group and the sera were used to compare the resulting HI values between immunoactive and immunosuppressed animals. The total fecal bacterial counts did not show any variation in the first group, while the immunosuppressed groups (2 and 3) demonstrated a gradual decrease. The HI titers were similarly affected and the immunosuppressed animals showed a gradual declining comparing with the first untreated control group. The HI titer of the first group was 2-⁶ , while nitrite group had a titer of 2-⁵ and the nitrate group had a titer of 2-⁴.