Browsing by Author "Kavas, Taner"

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Barium-lead-borosilicate glass containing lanthanum oxide: Fabrication, physical properties, and photon shielding characteristics
(Springer Heidelberg, 2022-02-01) Kuluöztürk, Zehra Nur; Kurtuluş, Recep; Kavas, Taner; Demir, Nilgün; DEMİR, NİLGÜN; Bursa Uludağ Üniversitesi/Fen Edebiyat Fakültesi/Psikoloji Bölümü.; 0000-0003-1070-8451; AAH-3156-2021
In our work, we studied the impact of lanthanum oxide (La2O3) on barium-lead-borosilicate (BLBS) glass systems in terms of physical properties and photon shielding characteristics. With this motivation, we aimed at synthesizing a BLBS glass system with a composition of 6Na(2)O-0.8MgO-0.25Al(2)O(3)-(55-y)SiO2-11B(2)O(3)-7.3CaO-13BaO-0.83SrO-5.75PbO-yLa(2)O(3), (y: 0, 5, 10, and 20 wt%), via traditional melting techniques. The fabricated glass samples, La-0 to La-20, were analyzed using some characterization techniques, including Archimedes' principle and spectroscopic gamma-rays experiment. According to the measurements, one can observe that all glass series show a transparent appearance irrespective of varying La2O3 content. On the other hand, the increasing La2O3 insertion ratio has a favorable influence on glass density (rho(glass)). That is, rho(glass) increases from 2.9419 to 3.3479 g.cm(-3) in subjection to the amount of La2O3 from 0 to 20 wt%. Similarly, molar volumes (V-m) for the La-series are found to be in an inclining behavior, namely, from 23.52 to 25.46 cm(3) mol(-1). With regards to the gamma-rays (356, 511, 661.7, 1173, 1275, and 1332 keV) attenuation characteristics, the linear attenuation coefficient (LAC) values obtained for the lowest energy by experimental and simulation methods for La-0 to La-20 samples were found in the range from 0.3298 to 0.4175 cm(-1) and 0.3349 to 0.3992 cm(-1), respectively. Similarly, the LAC for all energies increased as the La2O3 additive ratio increased; that is, the La-20 sample had the highest protection ability. In addition, we found out a good agreement among the FLUKA, XCOM, and experiments. Lastly, the LAC values of La2O3 added glass samples were compared with some concrete used for shielding, commercially available protection glasses, and some recent studies in the literature. The results showed that our glass samples, especially the La-20 glass sample, can be used as a potential candidate for photon shielding applications.
Preventive effects of bovine gallstone on murine colon neoplasia: Room for improvement?
(Bursa Uludağ Üniversitesi, 2023-05-04) Demirkan, İbrahim; Kavas, Ece; Bozkurt, Mehmet; Korkmaz, Musa; Kılıç, İbrahim; Kavas, Taner
Bovine gallstone (BGS) has been suggested to be used in the treatment of many diseases including neoplastic maladies in traditional medicine.Thus, this study aimed at evaluating the possible protective effects of BGS in mice colon tumor models. In the experiment, 8-week-old 30 male BALB/c mice weighing 25-30 g were randomly allocated into the control group (n=6), tumor group ((n=6; tumor induced by 1,2- dimethylhydrazine?[DMH]), BGS>DMH group (n=6; BGS given before DMH challenge), BGS//DMH group (n=6; simultaneous administration of BGS andDMH) and DMH>BGS group (n=6; tumor induced by DMH then BGS given). The colonic tumor was induced by weekly subcutaneous injectionof DMH at a 20 mg/kg/mouse dose for consecutive 11 weeks. BGS preparations were given to mice cyclically. Atypical cryptic foci formation inthe colon was examined by histopathological staining. The lowest rate of colon tumor was noted in BGS>DMH group where BGS was given priorto tumor challenge. In addition, simultaneous administration of DMH and BGS to mice inhibited tumor formation and development more significantlythan those in other groups (except for BGS>DMH group). It was concluded that BGS significantly prevented colonic tumor formationif given to subjects before or during tumor challenge however, therapeutic capacity of BGS was not promising in this study.