Browsing by Author "Bolca, Naile"
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Item Asit etyolojisinin belirlenmesinde radyolojik yöntemlerin yeri(Uludağ Üniversitesi, 2000) Bolca, Naile; Savcı, Gürsel; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.Amaç: Asit etyoiojisinin saptanmasında klinik yaklaşım, US ve BT gibi radyolojik yöntemlerin tanısal değerlerinin belirlemesi, Gereç ve yöntem: Asit etyoiojisinin belirlenmesi amacıyla, radyoloji departmanımıza gönderilen ya da başka bir nedenle araştırılma aşamasında asit saptanan yetişkin olgular çalışma kapsamına alındı. Böbrek fonksiyonları bozuk olgular çalışma kapsamı dışında tutuldu. Tüm olgular abdominopelvik US ve BT tetkikleri ile incelendi. Radyolojik yöntemlerle eş zamanlı olarak, abdominal parasentez yoluyla alınan asit materyalinin analizleri yapıldı. US ve BT tetkikleri, olguların klinik bulgularından ve patolojik sonuçlarından habersiz iki ayrı radyolojist tarafından kör olarak değerlendirildi. Değerlendirme sonuçları önceden standartize edilen formlara kaydedildi. Asit sıvısının laboratuvar analizlerine dayanarak her olgu için serum-asit albumin gradienti hesaplandı.US ve BT'de septa-debris varlığı, eşlik eden organ patolojisi, omental kek, barsak duvarı kalınlaşması, peritoneal implant, lenf nodu, portal ven çapı, safra kesesi duvar kalınlığı, plevral efüzyon, kollateral vasküleryapı ve kavernöz transformasyon araştırıldı. Tüm olguların patolojik tanısında, biyopsi veya cerrahi sonucu altın standart olarakalındı. Bulgular: Yaşları 25 ile 66 arasında değişen (ort. 53. 9±10. 9), 15'i erkek (% 53), 13'ü kadın (% 47) toplam 28 olgu çalışma kapsamında incelendi. Ondördünde (%50) malign, 14'ünde (%50) benign nedenlerin söz konusu olduğu olgularda; kesin tanı sekiz (%29) olguda cerrahi, 20 olguda (%71) biyopsi ile konuldu. Olguların tanıları tablo 4'te sunulmuştur. US ve BT arasında patolojileri saptama açısından yapılan karşılaştırmada, US"nin safra kesesi duvar kalınlığını değerlendirmede BT'ye oranla anlamlı derecede üstün olduğu tespit edildi (p< 0, 01). Bunun dışında kalan parametrelerin değerlendirilmesinde her iki yöntem arasında anlamlı fark saptanmadı (p>0, 05). Benign ve malign olgular açısından, patolojiler arasında farklılık araştırıldığında omental kalınlaşma (11 olgu, p<0.01), barsak duvar kalınlaşması (6 olgu, p<0.05) ve peritoneal implant oluşumu (8 olgu, p<0.05) malign olgularda benign olgulara oranla anlamlı derecede fazla bulundu. Safra kesesi duvarı kalınlaşması benignolgularda daha fazla tespit edildi (12 olgu, p<0.001). Malign ve benign nedenli asit olgularının asit dansitesi değerleri karşılaştırıldığında; malign olgularda kontrastsız kesitlerde ölçülen asit dansitesinin, benign olgularınınkinden daha yüksek olduğu belirlendi (p<0.01). Kontrast enjeksiyonu sonrası, bolus fazı ve 30. dakikada elde edilen denge fazına ait yapılan ölçümlerde her iki grup arasında asit sıvısının boyanmasında fark bulumadı (p>0.05) (tablo 6) SAAG değerleri 1.1 eşik değeri veüzerinde bulunan 14 olgudan 11 'i karaciğer sirozu olgusu, birisi otoimmün hepatit, ikisi karaciğer metastatik adenokanser tanısı aldı. SAAG değerleri 1.1 eşik değerinin altında bulunan 14 olgudan 12'sinde malign nedenler varken, ikisine tüberkülozperitoniti tanısı kondu. SAAG özgüllüğü %100 olarak bulundu. Sonuç: Benign-malign olguların ayrımında US ve BT'nin birbiriyle uyumlu sonuçlar vermektedir. Malign olgularda omental kalınlaşma, barsak duvarı kalınlaşması ve peritoneal implant daha sık görülmesine rağmen, bahsedilen bulgular ayırıcı tanıya yetecek kadar duyarlı değildir. Bu bulguların bir arada olduğu durumda, özgüllük artarak %98'e ulaşmaktadır.Item Assessment of severity and risk factors of post-thrombotic syndrome in vascular behcet disease: Muticentered retrospective study(Wiley, 2018-09) Aksoy, Aysun; Çolak, Seda; Omma, Ahmet; Ergelen, Rabia; Direskeneli, Haner; Alibaz, Fatma Öner; Yağız, Burcu; Coşkun, Belkıs Nihan; Bolca, Naile; Uludağ Üniversitesi/Tıp Fakültesi/Romatoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0003-0298-4157; AAG-7155-2021Publication Assessment of severity and risk factors of post-thrombotic syndrome in vascular Behcet disease: muticentered retrospective study(Clinical and Experimental Rheumatology, 2018) Aksoy, Aysun; Çolak, Seda; Omma, Ahmet; Ergelen, Rabia; Direskeneli, Rafi Haner; Alibaz, Öner Fatma; Yağız, Burcu; Coşkun, Belkıs Nihan; Bolca, Naile; Uludağ Üniversitesi/Tıp Fakültesi/Romatoloji Bilim Dalı; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Bilim Dalı; 0000-0003-0298-4157; JQW-5031-2023; AAG-7155-2021; EKW-9201-2022Item Bronchopulmonary sequestration: Radiologic findings(Elsevier Ireland, 2004-11) Bolca, Naile; Topal, Uğur; Bayram, Sami; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Kalp ve Damar Cerrahisi Anabilim Dalı.; 23569259700; 57001254100; 8705640100Bronchopulmonary sequestration (BPS) is a nonfunctioning bronchopulmonary tissue that is separate from the tracheobronchial tree and receives arterial blood from the systemic circulation. BPS has a wide spectrum of imaging findings. Surgery is generally indicated for the treatment of BPS. It is important to demonstrate the arterial supply and venous drainage of the sequestered segment preoperatively. Today, with the help of noninvasive imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI), preoperative diagnosis of BPS can be made easily, so, invasive techniques such as angiography are not required frequently. In this report, radiological findings of BPS were retrospectively reviewed.Item Brown tumors of the maxillary sinus and patella in a patient with primary hyperparathyroidism(Lippincott Williams & Wilkins, 2005) Duran, Cevdet; Ersoy, Canan; Bolca, Naile; Kıyıcı, Sinem; Yalçınkaya, Ulviye; Ertürk, Erdinç; Tuncel, Ercan; İmamoğlu, Şazi; Uludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji ve Metabolizma Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; AAH-8861-2021; AAJ-6536-2021; AAB-6174-2020; 12754039000; 6701485882; 13806674200; 12753880400; 6508300295; 7005488796; 7006929833; 6602297533Brown tumor is an important but rare complication of primary hyperparathyroidism. It is seen in approximately 1% of the cases. Common involvement areas are long bones, ribs, hand, skull, pelvic bones, and mandible. The maxillary sinus is a rare involvement site. Patellar bone involvement has not been reported. Because brown tumor and giant cell tumor have similar histopathologic findings, the differential diagnosis is important. We present a patient with ectopic parathyroid adenoma with multiple brown tumors located in uncommon areas such as the maxillary sinus and patella. A 54-year-old female patient was operated on 3 times for the suspicion of osteal giant cell tumor. After admission, the diagnosis of primary hyperparathyroidism was suggested by the clinical history. This was confirmed by biochemical, radiologic, and histopathologic determinations. Excision of an ectopic parathyroid adenoma normalized the metabolic status. The unusual brown tumor localizations were important in the differential diagnosis of lytic skeletal lesions.Item Clinical value of the malnutrition-inflammation-atherosclerosis syndrome for long-term prediction of cardiovascular mortality in patients with end-stage renal disease: A 5-year prospective study(Karger, 2008) Akdağ, İbrahim; Yılmaz, Yusuf; Kahvecioğlu, Serdar; Bolca, Naile; Ercan, İlker; Ersoy, Alparslan; Güllülü, Mustafa; Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji ve Romatoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; 0000-0002-0710-0923; 0000-0003-4518-5283; 0000-0002-2382-290X; AAH-5054-2021; 8342488100; 22936014300; 55956719500; 13806674200; 6603789069; 35612977100; 6602684544Background/Aim: Mortality resulting from cardiovascular disease in patients with end-stage renal disease (ESRD) is high. In this study we sought to investigate the clinical value of the malnutrition-inflammation-atherosclerosis (MIA) syndrome for long-term prediction of cardiovascular mortality in patients treated with ESRD. Methods: A total of 42 ESRD patients on hemodialysis were enrolled. Inflammatory markers and nutritional parameters were determined. Carotid atherosclerosis was investigated by ultrasonographically evaluated carotid intima-media thickness (cIMT). Mortality was evaluated at a 5-year follow-up. Results: No correlation was evident between nutritional markers and inflammatory indexes. cIMT was inversely correlated with predialysis serum albumin. In the overall population of 42 patients, 11 (26.2%) died of cardiovascular causes during follow-up. Kaplan-Meier survival curves indicate that cIMT (>= 0.9 mm), C-reactive protein (CRP) (>1 mg/dl), and serum albumin (<3.5 g/dl) predict cardiovascular death in patients with ESRD. Conclusions: We have demonstrated that cIMT, CRP and serum albumin predict long-term mortality in ERSD patients. Our study suggests that further investigation of the MIA syndrome will provide insights into the susceptibility to CVD in this patient group.Publication Efficacy of 0.1% tacrolimus ointment in chronic plaque psoriasis: A randomized double-blind placebo-controlled study(Deri Zuhrevi Hastaliklar Dernegi, 2015-01-01) Kaçar, Seval Dogruk; Kaçar, Emre; Baskan, Emel Bulbul; BÜLBÜL BAŞKAN, EMEL; Bolca, Naile; BOLCA TOPAL, NAİLE; Adım, Sadiman Balaban; BALABAN ADIM, ŞADUMAN; Tunalı, Şükran; Sarıcaoğlu, Hayriye; SARICAOĞLU, HAYRİYE; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Deri ve Zührevi Hastalıkları Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Patoloji Anabilim Dalı.; JLM-2426-2023; AAH-1388-2021Background and Design: Despite the development of effective systemic treatments and new biological agents for psoriasis nowadays, topical medications are still the mainstay of treatment. Topical calcineurin inhibitors are currently used in various skin diseases. We investigated the efficacy and safety of tacrolimus, which is an alternative in topical treatment, in comparison with the present medications in plaque psoriasis.Materials and Methods: This prospective double-blind placebo-controlled study was conducted in 24 patients with the diagnosis of plaque psoriasis who were seen in Uludag University Hospital dermatology outpatient clinic. 0.1% tacrolimus ointment, 0.1% mometasone furoate ointment, 0.005% calcipotriol ointment and placebo in encrypted bottles were randomly applied under occlusion to 27 psoriatic plaques in test chambers, every other day, for a period of 19 days. Clinic sum scores, side effects, and epidermal thickness measured by superficial ultrasound were noted before and after treatment in all microplaques. Besides, histopathologic scoring and epidermal thickness were measured in 9 patients at the end of the study.Results: The clinic sum scores and ultrasonographic epidermal thickness at the end were both significantly lower than the beginning values in all microplaques (p<0.05). The reduction in these two values with tacrolimus were significantly higher than that with placebo (p<0.001), but no difference was observed with calcipotriol (p=0.287, p=0.813, respectively). On the other hand, the reduction in these values with mometasone was significantly higher than with tacrolimus (p<0.05). Mometasone furoate was the most effective when the three ointments were compared with placebo in terms of total histopathological score and epidermal thickness.Conclusion: Tacrolimus ointment applied under occlusion is an alternative topical medication in the treatment of plaque psoriasis. Occlusion in practice requires patient compliance. Thus, studies to find a new formulation that will increase absorption of drug from thick psoriatic plaques are needed.Item Evaluation of different cerebral mass lesions by perfusion-weighted MR imaging(Wiley, 2006-06-30) Yıldırım, Nalan; Hakyemez, Bahattin; Cüneyt, Erdoğan; Bolca, Naile; Parlak, Mufit; Gökalp, Gökhan; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0002-3425-0740; AAG-8521-2021; AAI-2336-2021; AAI-2318-2021Purpose: To investigate the contribution of perfusion-weighted MR imaging (PWI) by using the relative cerebral blood volume (rCBV) ratio in the differential diagnosis of various intracranial space-occupying lesions. Materials and Methods: This study involved 105 patients with lesions (high-grade glioma (N = 26), low-grade glioma (N= 11), meningioma (N = 23), metastasis (N 25), hemangioblastoma (N = 6), pyogenic abscess (N 4), schwannoma (N = 5), and lymphoma. (N = 5)). The patients were examined with a T2*-weighted (T2*W) gradient-echo singleshot EPI sequence. The rCBV ratios of the lesions were obtained by dividing the values obtained from the normal white matter. Statistical analysis was performed with the Mann-Whitney U-test. A P-value less than 0.05 was considered statistically significant. Results: The rCBV ratio was 5.76 +/- 3.35 in high-grade gliomas, 1.69 +/- 0.51 in low-grade gliomas, 8.02 +/- 3.89 in meningiomas, 5.27 +/- 3.22 in metastases, 11.36 +/- 4.41 in hemangioblastomas, 0.76 +/- 0.12 in abscesses, 1.10 +/- 0.32 in lymphomas, and 3.23 +/- 0.81 in schwannomas. The rCBV ratios were used to discriminate between 1) high- and low-grade gliomas (P < 0.00 1), 2) hemangioblastomas and metastases (P < 0.05), 3) abscesses from high-grade gliomas and metastases (P < 0.001), 4) schwannomas and meningiomas (P < 0.001), 5) lymphomas from high-grade gliomas and metastases (P < 0.001), and 6) typical meningiomas and atypical meningiomas (P < 0.01). Conclusion: rCBV ratios can help discriminate intracranial space-occupying lesions by demonstrating lesion vascularity. It is possible to discriminate between 1) high- and low-grade gliomas, 2) hemangioblastomas and other intracranial posterior fossa masses, 3) abscesses from highgrade gliomas and metastases, 4) schwannomas and meningiomas, 5) lymphomas and high-grade gliomas and metastases, and 6) typical and atypical meningiomas.Item Miliary osteoma cutis of the face: Treatment with the needle microincision-extirpation method(Taylor & Francis, 2007) Başkan, Emel Bülbül; Turan, Hakan; Tunalı, Şükran; Toker, Semra Çıkman; Adım, Şaduman Balaban; Bolca, Naile; Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabiilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0002-0144-3263; AAH-1388-2021; 6602518817; 16835681500; 7004191748; 14054750900; 15730076300; 13806674200Multiple miliary osteoma cutis of the face represents primary extra-skeletal bone formation that arises within the skin of the face. Multiple miliary osteoma cutis of the face is a rare complication of chronic inflammatory acne vulgaris and has invasive and non-invasive treatment alternatives different from acne vulgaris. Invasive techniques should be simple, easy, and inexpensive, with minimal risk of scarring and pigmentation. We used a needle microincision-extirpation technique in a patient with multiple miliary osteoma cutis unresponsive to non-invasive treatment modalities. Skin overlying the papules was incised with a needle and then the calcificated papules were extirpated by using a small curettage device. Lesions were left to secondary healing. Results were quite good and cosmetically acceptable.Item Perihepatik lenfadenopati kronik hepatit b izleminde prognostik bir kriter olabilir mi?(Uludağ Üniversitesi, 2005-02-21) Özkan, Tanju Başarır; Sevinir, Betül; Bolca, Naile; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.Kronik B Hepatiti (KBH) tanısı alan hastalarda ultrasonografik olarak saptanan perihepatik LAP’nin antiviral tedavi ile gösterdiği değişimin KBH taşıyıcıları ile karşılaştırmalı olarak araştırılması planlandı. KBH tanısı alan 39 hasta ve KBH taşıyıcısı olan 23 hastada abdominal US incelemesi “e”antijeni(Ag) serokonversiyonu sonrası eş zamanlı olarak tekrarlandı. Perihepatik LAP boyutundaki değişimin ALT düzeyi, HBe Ag varlığı, HBV-DNA negatifleşmesiyle ilişkisi araştırıldı. KBH tanısı alan 39 hastadan 22’sinde (%56) US ile perihepatik LAP saptandı. 19 hastaya interferon tedavisi uygulandı. Bu hastalardan tedaviye yanıt veren 16’sında ve spontan serokonversiyon gösteren 1 hastada lenf nodu boyutlarında anlamlı küçülme saptandı (p<0.01). Tedaviye yanıt vermeyen 3 hastada lenf nodu boyutlarında anlamlı değişiklik olmadığı görüldü. Lenf nodu boyutundaki küçülmenin hastaların ALT düzeylerindeki düşme ile paralellik gösterdiği bulundu (p<0.05). KBH taşıyıcısı olan 23 hastanın 5’inde (% 21.7) perihepatik LAP saptandı. Bu hastaların 1 yıllık izleminde LAP boyutlarında anlamlı değişiklik saptanmadı (p>0.05).Perihepatik lenf nodu boyutunda küçülmenin interferon tedavisine iyi yanıtın veya viral klirensin indirekt bir göstergesi olarak kabul edilebileceği düşünüldü.Publication Predictors for the risk and severity of post-thrombotic syndrome in vascular Behcet's disease(Elsevier, 2021-02-04) Aksoy, Aysun; Çolak, Seda; Yağız, Burcu; Coşkun, Belkıs Nihan; Omma, Ahmet; Yıldız, Yasin; Sarı, Alper; Ataş, Nuh; Ilgın, Can; Karadağ, Ömer; Erden, Abdulsamet; Dalkılıç, Ediz; Bolca, Naile; Ergelen, Rabia; Onur, Mehmet Ruhi; Direskeneli, Haner; Alibaz-Öner, Fatma; YAĞIZ, BURCU; COŞKUN, BELKIS NİHAN; BOLCA TOPAL, NAİLE; DALKILIÇ, HÜSEYİN EDİZ; Bursa Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Romatoloji Bilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0003-0298-4157; JQW-5031-2023; AAG-7155-2021; CMF-4757-2022 ; EKW-9201-2022Objective: Deep vein thrombosis (DVT) of the lower extremities is the most common form of vascular involvement in Behcet disease (BD), frequently leading to post-thrombotic syndrome (PTS) as a disabling complication. We have described the clinical characteristics and predictors of PTS presence among patients with BD and lower extremity DVT. We also used venous Doppler ultrasound (US) examinations in our assessment. Methods: Patients with BD (n = 205; 166 men, 39 women; age 39 6 9.5 years) and a history of DVT were investigated. The Villalta scale was used to assess the presence and severity of PTS. Doppler US examinations were performed within 1 week of the clinical evaluation. The total number of vessels with reflux, thrombi, recanalization, and collateral vessels were calculated. Results: Of the 205 patients with BD, 62% had had PTS and 18% had had severe PTS. Patients with PTS had had greater reflux (P = .054) and thrombosis (P = .02) scores compared with patients without PTS. Treatment with anticoagulation (AC), immunosuppressive (IS) therapy, or AC combined with IS drugs did not affect the occurrence of PTS. However, patients treated with IS therapy, with or without AC drugs, had a decreased incidence of severe PTS compared with the AC-only group (P = .017). Patients treated with AC plus IS agents also had increased collateral scores compared with patients treated with only IS drugs. Interferon-a use seemed to provide better recanalization scores compared with azathioprine only (1.0 [range, 0-14] vs 2.5 [range, 0-10]; P = .010). Conclusions: Patients with BD and DVT have a high risk of developing severe PTS. IS treatment decreases the development of severe PTS. AC therapy might influence the course of PTS by increasing the collateral scores, and the use of interferon-a also increased recanalization scores. Routine assessment with Doppler US examinations could be helpful in the prediction of severe PTS.Publication Spontaneous remission of acromegaly due to apoplexy(Galenos Yayincilik, 2008-01-01) Duran, Cevdet; Ersoy, Canan; ERSOY, CANAN; Kıyıcı, Sinem; Bolca, Naile; BOLCA TOPAL, NAİLE; ERTÜRK, ERDİNÇ; İmamoğlu, Sazi; Tuncel, Ercan; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji Anabilim Dalı.; ursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0001-9560-180X; AAJ-6536-2021; AAH-8861-2021Pituitary apoplexy is a rare clinical syndrome characterized by sudden onset of headache and vomiting, accompanied by visual disturbance or ocular motility impairment and pituitary insufficiency. Pituitary apoplexy presenting with these symptoms is seen in approximately 3% of patients with surgically treated pituitary adenomas. In acromegalic patients, apoplexy can be related to some provocating factors and rarely may be spontaneous. We present the case of an acromegalic patient with spontaneous remission after apoplexy. A 39-year-old male patient had transsphenoidal microsurgery for acromegaly in 1994 but remission was not achieved. After a 10-year period without follow-up, he experienced severe headache, nausea, vomiting, photophobia, and visual disturbance in July 2005 and scheduled an appointment with an ophthalmologist. His complaints ceased spontaneously within weeks. In October 2005, sellar MRI examination revealed a 3x2.5 cm mass of adenomatous tissue with necrosis. On admission to our clinic in November 2005, visual acuity, visual fields, and ocular motility, were normal; but results of laboratory tests revealed panhypopituitarism. He was thought to have apoplexy of a growth hormone secreting tumor, and hormone replacement therapy was initiated for panhypopituitarism. Because his symptoms had regressed, surgery was not considered. On rare occasions, acromegaly spontaneously remits after apoplexy, resulting in improved control of the functional adenoma without surgical intervention.Item Warfarin-induced chest wall and breast hematoma in an elderly female patient with atrial fibrillation: Original image(Ortadogu Ad Pres & Publ Co, 2008-12) Özdemir, Bülent; Bayram, Ahmet Sami; Bolca, Naile; Kumbay, Ethem; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0003-0684-0900; JHE-3353-2023; ABB-7580-2020; EKW-9201-2022; DAV-9436-2022; 7004168959; 8347194000; 13806674200; 6507775316Atrial fibrillation is the most common sustained cardiac rhythm disorder. Current treaatment guidelines recommend long-term oral anticoagulation with a vitamin K antagonist, such as warfarin, in patients with atrial fibrillation who are at moderate to high risk of stroke. Bleeding is a common side effect of warfarin. The risk of severe bleeding is a small but definite (1-2% annually) result of warfarin use. Risk of bleeding is augmented if the international normalization ratio (INR) is high. We presented a case with warfarin induced chest wall and breast hematoma, which is a rare condition.