Capecitabine-induced cardiotoxicity mimicking myocardial infarction
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Date
2009-08
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Bohn Stafleu van Loghum
Abstract
Capecitabine, a fluoropyrimidine derivative, is an orally administered drug that delivers 5-fluorouracil (5-FU) selectively to the tumour. The drug has demonstrated activity in metastatic colorectal cancer. We describe a male patient receiving capecitabine therapy with typical chest pain and electrocardiographic changes consistent with ST-segment elevation myocardial infarction. Capecitabine-induced cardiotoxicity may develop in patients who have had a previous episode of 5-FU-induced cardiotoxicity. Capecitabine-induced cardiotoxicity is a rare condition that may lead to diagnostic and therapeutic dilemmas.
Description
Keywords
Capecitabine, Cardiotoxicity, Myocardial infarction, Cardiovascular system & cardiology
Citation
Şentürk, T. vd. (2009). "Capecitabine-induced cardiotoxicity mimicking myocardial infarction". Netherlands Heart Journal, 17(7-8), 277-280.