Alt solunum yolu enfeksiyonu tanısıyla yatırılan hastalarda respiratuvar sinsityal virüs enfeksiyonu sıklığı ve klinik özellikleri
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Date
2015-02-17
Authors
Gülcan, Gülcihan
Turan, Özden
Türkmenoğlu, Yelda
Türkkan, Emine
Köse, Gülşen
Journal Title
Journal ISSN
Volume Title
Publisher
Uludağ Üniversitesi
Abstract
Giriş: Bu çalışmada hastanemize alt solunum yolu enfeksiyonu (ASYE) tanısı ile yatırılan bebeklerde respiratuvar sinsityal virüs (RSV) enfeksiyonu sıklığı ve klinik özelliklerinin belirlenmesi amaçlandı. Gereç ve Yöntem: Bir Aralık 2012-1 Mart 2013 tarihleri arasında ASYE tanısı ile yatırılan ve nazofarengeal sürüntü örneklerinde enzim immünoassey yöntemiyle etken olarak RSV bakılan 1-24 ay arası 170 hastanın dosyaları geriye dönük incelenerek klinik ve laboratuvar özellikleri değerlendirildi. Bulgular: Hastaların %37,1’inde RSV enfeksiyonu saptandı. RSV (+) olgularda RSV (-) olgulara göre yaşı 6 ayın altında olanların oranı istatistiksel olarak anlamlı derecede yüksek saptandı. RSV (+) ve RSV (-) olgular arasında cinsiyet, akciğer grafisinde infiltrasyon, C-reaktif protein pozitifliği, lökosit değerleri, trombosit sayısı, yetersiz anne sütü alma, ailesinde solunum yolu enfeksiyonu varlığı, annede ve ailede sigara içme öyküsü, başvuru yakınmaları bakımından istatistiksel olarak anlamlı fark saptanmadı. Sonuç: Çalışmamızda 1-24 ay arası ASYE tanısı ile yatırılan hastalarda yüksek oranda (%37,1) literatürle uyumlu olarak RSV enfeksiyonu saptandı. RSV enfeksiyonunun belirlenmesinin gerekli izolasyon önlemlerinin alınarak hastalar arası bulaşmanın engellenebilmesini sağlayacağını ve gereksiz antibiyotik kullanımının azaltılabilmesine katkıda bulunacağını düşünüyoruz.
Introduction: In this study, we aimed to investigate the frequency and clinical features of respiratory syncytial virus (RSV) infection among infants hospitalized with the diagnosis of lower respiratory tract infection. Materials and Methods: The study was conducted between 1 December 2012 and 1 March 2013 in our pediatric clinic. A total of 170 children between 1-24 months of age with lower respiratory tract infection were included. Their clinical and laboratory findings were analyzed retrospectively. The detection of RSV antigen was carried out by immunoassay method on nasopharyngeal swabbing samples. Results: RSV infection was determined in 37.1% of the patients. RSV (+) patients under the age of 6 months was statistically significantly higher than RSV (-) patients. In RSV (+) and RSV (-) patients there was no statistically significantly difference in gender, infiltration in chest radiography, C-reactive protein positivity, white blood cell count, platelets, insufficient breast feeding, three or more than three siblings, history of upper respiratory tract infection in the family, maternal and family smoke exposure. Conclusions: In this study, patients between 1-24 months of the age admitted to the hospital with a diagnosis of lower respiratory tract infections, that highly consistent with the literature (37.1%) were RSV infection. In the determination of RSV infection, taking the necessary measures in isolation of this infection provide access block transmission between patients and contribute reducing unnecessary use of antibiotics.
Introduction: In this study, we aimed to investigate the frequency and clinical features of respiratory syncytial virus (RSV) infection among infants hospitalized with the diagnosis of lower respiratory tract infection. Materials and Methods: The study was conducted between 1 December 2012 and 1 March 2013 in our pediatric clinic. A total of 170 children between 1-24 months of age with lower respiratory tract infection were included. Their clinical and laboratory findings were analyzed retrospectively. The detection of RSV antigen was carried out by immunoassay method on nasopharyngeal swabbing samples. Results: RSV infection was determined in 37.1% of the patients. RSV (+) patients under the age of 6 months was statistically significantly higher than RSV (-) patients. In RSV (+) and RSV (-) patients there was no statistically significantly difference in gender, infiltration in chest radiography, C-reactive protein positivity, white blood cell count, platelets, insufficient breast feeding, three or more than three siblings, history of upper respiratory tract infection in the family, maternal and family smoke exposure. Conclusions: In this study, patients between 1-24 months of the age admitted to the hospital with a diagnosis of lower respiratory tract infections, that highly consistent with the literature (37.1%) were RSV infection. In the determination of RSV infection, taking the necessary measures in isolation of this infection provide access block transmission between patients and contribute reducing unnecessary use of antibiotics.
Description
Keywords
Alt solunum yolu enfeksiyonu, Respiratuvar sinsityal virüs, Hızlı tanı, Antijen tarama, Lower respiratory tract infections, Respiratory syncytial virus, Rapid diagnosis, Antibody screening
Citation
Gülcan, Gülcihan. vd. (2015). "Alt solunum yolu enfeksiyonu tanısıyla yatırılan hastalarda respiratuvar sinsityal virüs enfeksiyonu sıklığı ve klinik özellikleri". Güncel Pediatri, 13(2), 97-103.